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WormBase Tree Display for Expr_pattern: Expr10629

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Name Class

Expr10629Expression_ofGeneWBGene00028298
Reflects_endogenous_expression_ofWBGene00028298
Expression_dataLife_stageWBls:0000041
WBls:0000023
WBls:0000020
Anatomy_termWBbt:0004017Certain
RemarkUbiquitously expressed.
GO_termGO:0005783
Subcellular_localizationEMC-6 primarily localize to the ER.
TypeReporter_gene
PatternIn mosaic animals, GFP was detected in almost all tissues, including neurons and muscle cells. Transgenes driving GFP expression under the control of the 263-bp promoter sequence used for emc-6 rescue experiments induced lethality and did not transmit GFP expression after one generation. To bypass this technical issue, the authors characterized the expression pattern of the Caenorhabditis briggsae ortholog of emc-6 (Cb-emc-6) in C. elegans. Interestingly, transgenic expression of Cb-emc- 6 was nontoxic in C. elegans. GFP expression was observed in every tissue from the threefold stage to adulthood. Altogether, these results suggest that emc-6 is ubiquitously expressed.
SpeciesCaenorhabditis briggsae
ReferenceWBPaper00042060
TransgeneWBTransgene00017720
WBTransgene00017721
WBTransgene00017722
WBTransgene00017723
WBTransgene00017724