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WormBase Tree Display for Expr_pattern: Expr10575

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Name Class

Expr10575Expression_ofGeneWBGene00004775
Reflects_endogenous_expression_ofWBGene00004775
Expression_dataGO_termGO:0005634
GO:0005694
GO:0005813
GO:0060473
Subcellular_localizationDuring oocyte maturation, cytoplasmic separase rapidly accumulated in the nucleus on homologous chromosomes. Separase also localized to unusual filaments distributed throughout the cortex. Before anaphase onset, separase was lost from these filamentous structures and accumulated on cortical vesicles. Separase co-localized with WGA-labeled cortical granules during anaphase I. Separase-labeled vesicles were lost during anaphase I, beginning in the region near the meiotic spindle. In mitotic embryos, separase localized to centrosomes, chromosomes and a diffuse cloud around the metaphase plate and anaphase spindle.
TypeAntibody
Reporter_gene
PatternSEP-1 localizes on cortical granules.
ReferenceWBPaper00031064
TransgeneWBTransgene00007698
Antibody_infoWBAntibody00001311