WormBase Tree Display for Expr_pattern: Expr10043

Expr10043 Expression_of: Gene: WBGene00006342
    Reflects_endogenous_expression_of: WBGene00006342
  Expression_data: Life_stage: WBls:0000024
      WBls:0000003
      WBls:0000038
      WBls:0000027
      WBls:0000035
      WBls:0000041
    Anatomy_term: WBbt:0003681 Certain
      WBbt:0003724 Certain
      WBbt:0003739 Certain
      WBbt:0003740 Certain
      WBbt:0005319 Certain
    GO_term: GO:0005634
      GO:0005737
  Subcellular_localization: Full-length (isoform-a) SUP-37::GFP and SUP- 37::mcherry fusion proteins localize predominantly to nuclei during late stages of embryogenesis. Expression of these constructs was, however, relatively dim and quite variable as compared with the sup-37 transcriptional reporters. Expression of the SUP-37 translational reporters was also occasionally detected in both the cytoplasm and nuclei of early-stage embryos at time points preceding morphogenesis.
  Type: Reporter_gene
  Pattern: All tested strains showed strong enrichment of sup-37 reporter expression within the pharynx beginning at the ~500-cell stage of embryogenesis and continuing throughout larval development and adulthood. In addition, weak-to-modest levels of sup-37 reporter expression were observed in all other cell types.
    In larval and adult stages, the full-length SUP-37::mCherry was expressed in the pharyngeal muscle groups pm3, pm4, and pm6, but not consistently in other cells of the pharynx. In addition, SUP-37::mCherry expression was faint but detectable in the spermatheca of adult hermaphrodites. Expression of SUP-37::mCherry was not detected in the somatic gonad sheath cells, which also play a role in ovulation.
  Picture: WBPicture0000012714
    WBPicture0000012715
  Reference: WBPaper00041001
  Transgene: WBTransgene00031342
    WBTransgene00031699
    WBTransgene00031700