WormBase Tree Display for Variation: WBVar02125476

WBVar02125476 Name: Public_name: tm6644
    Other_name: Y41D4B.12a.1:c.18_358del
      CE27623:p.Asp7ArgfsTer11
      Y41D4B.12b.1:c.-186_103del
      Y41D4B.12a.2:c.18_358del
    HGVSg: CHROMOSOME_IV:g.1603005_1603345del
  Sequence_details: SMap: S_parent: Sequence: Y41D4B
    Flanking_sequences: caaatttcagataatgaattatgagaaaat acgctggggaatgtattggcgagcaagaag
    Mapping_target: Y41D4B
    Source_location: 7 CHROMOSOME_IV 1603004 1603346 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Deletion
    PCR_product: tm6644_external
      tm6644_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 6644
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00021515
    Transcript: Y41D4B.12b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,start_lost,5_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y41D4B.12b.1:c.-186_103del
        cDNA_position: 21-309
        CDS_position: ?-103
        Protein_position: ?-35
        Intron_number: 2/5
        Exon_number: 1-3/6
      Y41D4B.12a.1 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: Y41D4B.12a.1:c.18_358del
        HGVSp: CE27623:p.Asp7ArgfsTer11
        cDNA_position: 21-361
        CDS_position: 18-358
        Protein_position: 6-120
        Exon_number: 2/5
        Codon_change: atTGATAGCACAATTCCCGGGCCAGGAATCTCTGAAACCGACTGGAATGACGTATTCGAAGGATGTAACTGCGAGGCTGAGTGCTCTTCAGCCGCCGGTTGCTCGTGTCTAATCAATAAAATCGATAATTACACTGTCGATGGAAAAATCAATAAATCATCGGAGCTTCTAATCGAGTGCTCCGATCAATGTGCCTGCATACTGCTCCCAACTTCATGTAGGAATCGAGTTGTGCAATGTGGACCACAGAAAAAGCTGGAAATTTTCAGCACTTGTGAGATGGCAAAAGGATTCGGAGTTCGAGCCGGCGAGCAGATAGCCGCCGGCGAATTTGTGTGCGAATac/atac
        Amino_acid_change: IDSTIPGPGISETDWNDVFEGCNCEAECSSAAGCSCLINKIDNYTVDGKINKSSELLIECSDQCACILLPTSCRNRVVQCGPQKKLEIFSTCEMAKGFGVRAGEQIAAGEFVCEY/IX
      Y41D4B.12a.2 VEP_consequence: frameshift_variant
        VEP_impact: HIGH
        HGVSc: Y41D4B.12a.2:c.18_358del
        HGVSp: CE27623:p.Asp7ArgfsTer11
        cDNA_position: 1349-1689
        CDS_position: 18-358
        Protein_position: 6-120
        Exon_number: 2/5
        Codon_change: atTGATAGCACAATTCCCGGGCCAGGAATCTCTGAAACCGACTGGAATGACGTATTCGAAGGATGTAACTGCGAGGCTGAGTGCTCTTCAGCCGCCGGTTGCTCGTGTCTAATCAATAAAATCGATAATTACACTGTCGATGGAAAAATCAATAAATCATCGGAGCTTCTAATCGAGTGCTCCGATCAATGTGCCTGCATACTGCTCCCAACTTCATGTAGGAATCGAGTTGTGCAATGTGGACCACAGAAAAAGCTGGAAATTTTCAGCACTTGTGAGATGGCAAAAGGATTCGGAGTTCGAGCCGGCGAGCAGATAGCCGCCGGCGAATTTGTGTGCGAATac/atac
        Amino_acid_change: IDSTIPGPGISETDWNDVFEGCNCEAECSSAAGCSCLINKIDNYTVDGKINKSSELLIECSDQCACILLPTSCRNRVVQCGPQKKLEIFSTCEMAKGFGVRAGEQIAAGEFVCEY/IX
  Isolation: Mutagen: TMP/UV
  Genetics: Map: IV
  Description: Phenotype_not_observed: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as homozygous viable by the National Bioresource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
            Laboratory_evidence: FX
  Remark: 45902/45903-46243/46244 (341 bp deletion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele