WormBase Tree Display for Variation: WBVar01474346

WBVar01474346 Name: Public_name: tm6329
    Other_name: CE09197:p.Leu256_Leu517delinsHis
      F07A5.7a.1:c.767_1550delinsA
      F07A5.7a.2:c.767_1550delinsA
    HGVSg: CHROMOSOME_I:g.7378736_7379519delinsT
  Sequence_details: SMap: S_parent: Sequence: F07A5
    Flanking_sequences: gcggcaataagtctgtcgatttcgaattga gttgggagcgctcctgaaatttcaacgttc
    Mapping_target: F07A5
    Source_location: 7 CHROMOSOME_I 7378735 7379520 Inferred_automatically: National_Bioresource_Project
    Type_of_mutation: Insertion: T
      Deletion
    PCR_product: tm6329_external
      tm6329_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00007595
    Laboratory: FX
    Author: Mitani S
    DB_info: Database: National_Bioresource_Project seq 6329
    NBP_allele
    Status: Live
  Affects: Gene: WBGene00006754
    Transcript: F07A5.7a.1 VEP_consequence: protein_altering_variant
        VEP_impact: MODERATE
        HGVSc: F07A5.7a.1:c.767_1550delinsA
        HGVSp: CE09197:p.Leu256_Leu517delinsHis
        cDNA_position: 881-1664
        CDS_position: 767-1550
        Protein_position: 256-517
        Exon_number: 9/14
        Codon_change: cTTCAATCTCAACTCCACCAGGTTCAGCTCGAGCTCGACTCGGTCCGCACCGCTCTCGATGAGGAGTCGATTGCCCGTTCCGATGCTGAGCACAAGCTCAACCTTGCCAACACTGAGATCACCCAGTGGAAGAGCAAGTTCGATGCTGAGGTCGCCCTTCACCACGAAGAAGTTGAGGATCTCCGCAAGAAGATGCTCCAGAAGCAAGCTGAGTATGAAGAGCAAATCGAGATCATGCTCCAGAAGATTTCTCAACTCGAGAAGGCCAAGTCTCGTCTTCAATCTGAGGTCGAGGTTCTTATCGTTGATCTTGAGAAGGCCCAGAACACCATTGCTCTCTTGGAGCGTGCCAGAGAACAACTCGAGAGACAAGTTGGAGAACTCAAGGTCCGTATCGATGAGATCACTGTTGAACTCGAAGCTGCTCAACGCGAACTCCGTGCCGTCAATGCTGAGCTCCAGAAGATGAAGCATTTGTACGAGAAGGCTGTCGAACAGAAGGAGGCTCTTGCTCGCGAGAACAAGAAGCTCCACGACGAACTTCACGAAGCCAAGGAGGCTCTTGCCGACGCCAACCGCAAGCTCCACGAGCTCGACCTCGAGAACGCCCGTCTTGCCGGAGAAATCCGTGAGCTCCAGACTGCCCTCAAGGAGGCTGATGCTCAACGCCGTGACGCCGAAAACCGCGCTCAACGTGCCCTTGCTGAGCTCCAGGCTCTTCGCATCGAAATGGAACGTCGTCTCCAAGAGAAGGAAGAAGAGATGGAGGCTCTTCGCAAGAACCTt/cAt
        Amino_acid_change: LQSQLHQVQLELDSVRTALDEESIARSDAEHKLNLANTEITQWKSKFDAEVALHHEEVEDLRKKMLQKQAEYEEQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNTIALLERAREQLERQVGELKVRIDEITVELEAAQRELRAVNAELQKMKHLYEKAVEQKEALARENKKLHDELHEAKEALADANRKLHELDLENARLAGEIRELQTALKEADAQRRDAENRAQRALAELQALRIEMERRLQEKEEEMEALRKNL/H
      F07A5.7a.2 VEP_consequence: protein_altering_variant
        VEP_impact: MODERATE
        HGVSc: F07A5.7a.2:c.767_1550delinsA
        HGVSp: CE09197:p.Leu256_Leu517delinsHis
        cDNA_position: 881-1664
        CDS_position: 767-1550
        Protein_position: 256-517
        Exon_number: 9/13
        Codon_change: cTTCAATCTCAACTCCACCAGGTTCAGCTCGAGCTCGACTCGGTCCGCACCGCTCTCGATGAGGAGTCGATTGCCCGTTCCGATGCTGAGCACAAGCTCAACCTTGCCAACACTGAGATCACCCAGTGGAAGAGCAAGTTCGATGCTGAGGTCGCCCTTCACCACGAAGAAGTTGAGGATCTCCGCAAGAAGATGCTCCAGAAGCAAGCTGAGTATGAAGAGCAAATCGAGATCATGCTCCAGAAGATTTCTCAACTCGAGAAGGCCAAGTCTCGTCTTCAATCTGAGGTCGAGGTTCTTATCGTTGATCTTGAGAAGGCCCAGAACACCATTGCTCTCTTGGAGCGTGCCAGAGAACAACTCGAGAGACAAGTTGGAGAACTCAAGGTCCGTATCGATGAGATCACTGTTGAACTCGAAGCTGCTCAACGCGAACTCCGTGCCGTCAATGCTGAGCTCCAGAAGATGAAGCATTTGTACGAGAAGGCTGTCGAACAGAAGGAGGCTCTTGCTCGCGAGAACAAGAAGCTCCACGACGAACTTCACGAAGCCAAGGAGGCTCTTGCCGACGCCAACCGCAAGCTCCACGAGCTCGACCTCGAGAACGCCCGTCTTGCCGGAGAAATCCGTGAGCTCCAGACTGCCCTCAAGGAGGCTGATGCTCAACGCCGTGACGCCGAAAACCGCGCTCAACGTGCCCTTGCTGAGCTCCAGGCTCTTCGCATCGAAATGGAACGTCGTCTCCAAGAGAAGGAAGAAGAGATGGAGGCTCTTCGCAAGAACCTt/cAt
        Amino_acid_change: LQSQLHQVQLELDSVRTALDEESIARSDAEHKLNLANTEITQWKSKFDAEVALHHEEVEDLRKKMLQKQAEYEEQIEIMLQKISQLEKAKSRLQSEVEVLIVDLEKAQNTIALLERAREQLERQVGELKVRIDEITVELEAAQRELRAVNAELQKMKHLYEKAVEQKEALARENKKLHDELHEAKEALADANRKLHELDLENARLAGEIRELQTALKEADAQRRDAENRAQRALAELQALRIEMERRLQEKEEEMEALRKNL/H
      F07A5.7b.1 VEP_consequence: coding_sequence_variant,5_prime_UTR_variant
        VEP_impact: MODIFIER
        cDNA_position: ?-593
        CDS_position: ?-593
        Protein_position: ?-198
        Exon_number: 1/4
  Isolation: Mutagen: TMP/UV
  Genetics: Map: I
  Description: Phenotype: WBPhenotype:0000062 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National BioResource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Person_evidence: WBPerson7743
        Curator_confirmed: WBPerson712
        Remark: Classified as lethal OR sterile by the National BioResource Project of Japan. Person_evidence: WBPerson7743
            Curator_confirmed: WBPerson712
  Remark: 29881/29882-T-30665/30666 (784 bp deletion + 1 bp insertion)
    This knockout was generated by the National Bioresource Project, Tokyo, Japan, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence: WBPaper00041807
  Method: NBP_knockout_allele