WormBase Tree Display for Variation: WBVar00266484

WBVar00266484 Evidence: Paper_evidence: WBPaper00005563
  Name: Public_name: tz2
    Other_name: Y41C4A.4a.1:c.858+3_*101del
      Y41C4A.4g.1:c.1167+3_*101del
      Y41C4A.4e.1:c.801+3_*101del
      Y41C4A.4d.1:c.876+3_*101del
      Y41C4A.4f.1:c.450+3_*101del
    HGVSg: CHROMOSOME_III:g.11692677_11693655del
  Sequence_details: SMap: S_parent: Sequence: Y41C4A
    Flanking_sequences: agcgaaagagtgccgcagaaaaaagaaggt atttcctaatttttgaaagaaaaaaaattg
    Mapping_target: Y41C4A
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain (2)
    Laboratory: YT
    Status: Live
  Affects: Gene: WBGene00000793
    Transcript: Y41C4A.4e.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y41C4A.4e.1:c.801+3_*101del
        cDNA_position: ?-1082
        Intron_number: 7/8
        Exon_number: 8-9/9
      Y41C4A.4g.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y41C4A.4g.1:c.1167+3_*101del
        cDNA_position: ?-1388
        Intron_number: 5/6
        Exon_number: 6-7/7
      Y41C4A.4b.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 6/6
        Exon_number: 7/7
      Y41C4A.4a.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y41C4A.4a.1:c.858+3_*101del
        cDNA_position: ?-1181
        Intron_number: 7/8
        Exon_number: 8-9/9
      Y41C4A.4d.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y41C4A.4d.1:c.876+3_*101del
        cDNA_position: ?-1197
        Intron_number: 7/8
        Exon_number: 8-9/9
      Y41C4A.4f.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: Y41C4A.4f.1:c.450+3_*101del
        cDNA_position: ?-937
        Intron_number: 4/5
        Exon_number: 5-6/6
      Y41C4A.4c.1 VEP_consequence: splice_acceptor_variant,coding_sequence_variant,3_prime_UTR_variant,intron_variant
        VEP_impact: HIGH
        Intron_number: 6/6
        Exon_number: 7/7
    Interactor: WBInteraction000546931
  Genetics: Interpolated_map_position: III 11.7926
  Description: Phenotype (10)
    Phenotype_not_observed: WBPhenotype:0002199 Paper_evidence: WBPaper00049050
        Curator_confirmed: WBPerson2987
        Remark: "However, neither crh-1 mutants that lacked a C. elegans CREB homolog (Nishida et al., 2011) nor unc-43 mutants that lacked the C. elegans CaMKII ortholog (Reiner et al., 1999) showed a severe defect in the variable calcium response of AFD (Figure S2B)." Paper_evidence: WBPaper00049050
            Curator_confirmed: WBPerson2987
        EQ_annotations: Anatomy_term: WBbt:0005662 PATO:0000460 Paper_evidence: WBPaper00049050
                Curator_confirmed: WBPerson2987
        Phenotype_assay: Genotype: njIs24[gcy-8p::GCaMP3, gcy-8p::TagRFP] (I); Parent strain: IK0972 Paper_evidence: WBPaper00049050
              Curator_confirmed: WBPerson2987
      WBPhenotype:0002469 Paper_evidence: WBPaper00039821
        Curator_confirmed: WBPerson5364
        Remark: Figure 1, crh-1(tz2) mutant worms can habituate to repeated mechanosensory (tap) stimuli Paper_evidence: WBPaper00039821
            Curator_confirmed: WBPerson5364
  Reference: WBPaper00039821
    WBPaper00039855
    WBPaper00040253
    WBPaper00010064
    WBPaper00005563
    WBPaper00036296
    WBPaper00046360
    WBPaper00049050
    WBPaper00041586
    WBPaper00049891
  Method: Deletion_allele