WormBase Tree Display for Variation: WBVar00241242
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| WBVar00241242 | Name | Public_name | qm34 | |||||
|---|---|---|---|---|---|---|---|---|
| Sequence_details | SeqStatus | Pending_curation | ||||||
| Variation_type | Allele | |||||||
| Origin | Species | Caenorhabditis elegans | ||||||
| Strain | WBStrain00026656 | |||||||
| Laboratory | MQ | |||||||
| Status | Live | |||||||
| Affects | Gene | WBGene00020375 | ||||||
| Description | Phenotype | WBPhenotype:0000050 | Paper_evidence | WBPaper00046712 | ||||
| Person_evidence | WBPerson261 | |||||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPerson3276 | ||||||||
| WBPerson7529 | ||||||||
| Remark | some embryonic lethality; full zygotic and maternal rescue | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Figure 1E describe the distribution of the embryonic lethal phenotypes | Paper_evidence | WBPaper00046712 | ||||||
| Curator_confirmed | WBPerson3276 | |||||||
| ~80% of pigv-1(qm34) embryos arrested development during the elongation phase of morphogenesis, exhibiting internal cysts and/or surface ruptures. Closer examination of the defects revealed them all to be the result of breaches in epithelial tissues: cysts formed in the intestine and excretory canal, and ruptures occurred through epidermal cells, suggesting weakening of the epithelial membrane or membrane-cortex connection. | Paper_evidence | WBPaper00046712 | ||||||
| Curator_confirmed | WBPerson7529 | |||||||
| Penetrance | Incomplete | Paper_evidence | WBPaper00046712 | |||||
| Curator_confirmed | WBPerson3276 | |||||||
| Recessive | Paper_evidence | WBPaper00046712 | ||||||
| Curator_confirmed | WBPerson3276 | |||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00046712 | |||||
| Curator_confirmed | WBPerson3276 | |||||||
| Temperature_sensitive | Heat_sensitive | Paper_evidence | WBPaper00046712 | |||||
| Curator_confirmed | WBPerson3276 | |||||||
| Maternal | With_maternal_effect | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000054 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | very high larval lethality; full zygotic and maternal rescue | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Maternal | With_maternal_effect | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000071 | Person_evidence | WBPerson261 | ||||||
| Curator_confirmed | WBPerson712 | |||||||
| Remark | head frequently deformed because buccal opening displaced ventrally, dorsally or laterally | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| Maternal | With_maternal_effect | Person_evidence | WBPerson261 | |||||
| Curator_confirmed | WBPerson712 | |||||||
| WBPhenotype:0000072 | Paper_evidence | WBPaper00046712 | ||||||
| Curator_confirmed | WBPerson3276 | |||||||
| Remark | Figure 1A shows the morphology defect at the anterior part of qm34 L1 larva | Paper_evidence | WBPaper00046712 | |||||
| Curator_confirmed | WBPerson3276 | |||||||
| Penetrance | Incomplete | Paper_evidence | WBPaper00046712 | |||||
| Curator_confirmed | WBPerson3276 | |||||||
| Recessive | Paper_evidence | WBPaper00046712 | ||||||
| Curator_confirmed | WBPerson3276 | |||||||
| Variation_effect | Hypomorph_reduction_of_function | Paper_evidence | WBPaper00046712 | |||||
| Curator_confirmed | WBPerson3276 | |||||||
| Temperature_sensitive | Heat_sensitive | Paper_evidence | WBPaper00046712 | |||||
| Curator_confirmed | WBPerson3276 | |||||||
| Reference | WBPaper00046712 | |||||||
| Method | Allele |
