WormBase Tree Display for Variation: WBVar00239435

WBVar00239435 Evidence: Paper_evidence: WBPaper00031945
  Name: Public_name: pk2279
  Sequence_details: Mapping_target: F33H2
    Type_of_mutation: Substitution: g a
    SeqStatus: Pending_curation
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: NL
    Status: Live
  Affects: Gene: WBGene00001049
  Description: Phenotype: WBPhenotype:0001760 Paper_evidence: WBPaper00031945
        Curator_confirmed: WBPerson712
        Remark: MonoG or G-tracts were deleted at an increased rate, in all somatic tissues, as demonstrated by the expression of B-galactosidase as an indicator of a DNA rearrangement bringing a LacZ start codon in-frame with the downstream ORF. MonoA tracts were not susceptible to deletions. An increase in deletion frequency over wild-type was observed for the endogenous qua375 sequence as determined by PCR. At least 24 populations of 5 animals were assayed. Paper_evidence: WBPaper00031945
            Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: pkIs2165[pRP1878: hsp-16.41::ATG-(C)23-stops-LacZ unc-119] or pkIs2172 [pRP1889: hsp-16.41::ATG-(monoA)-stops-LacZ unc-119] Paper_evidence: WBPaper00031945
              Curator_confirmed: WBPerson712
  Reference: WBPaper00031945
  Method: Substitution_allele