WormBase Tree Display for Variation: WBVar00144001

WBVar00144001 Evidence: Paper_evidence: WBPaper00031068
  Name: Public_name: e1430
    Other_name: CE25115:p.Arg157Ter
      T19B4.7.1:c.469C>T
    HGVSg: CHROMOSOME_I:g.5687164G>A
  Sequence_details (5)
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00004390
      WBStrain00022025
      WBStrain00022040
      WBStrain00022045
    Laboratory: CB
    Status: Live
  Affects: Gene: WBGene00006776
    Transcript: T19B4.7.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: T19B4.7.1:c.469C>T
        HGVSp: CE25115:p.Arg157Ter
        cDNA_position: 532
        CDS_position: 469
        Protein_position: 157
        Exon_number: 5/19
        Codon_change: Cga/Tga
        Amino_acid_change: R/*
    Interactor (11)
  Genetics: Interpolated_map_position: I 0.317602
    Mapping_data: In_multi_point: 244
        290
      In_pos_neg_data: 4018
        4028
        4032
        4038
        4045
        4052
        4059
        4066
  Description: Phenotype (8)
    Phenotype_not_observed: WBPhenotype:0000104 Paper_evidence: WBPaper00033081
          WBPaper00035146
        Curator_confirmed: WBPerson2021
        Remark: Polarity is normal in all mutants Paper_evidence: WBPaper00033081
            Curator_confirmed: WBPerson2021
          Mutants do not alter the asymmetric localization of UNC-40 Paper_evidence: WBPaper00035146
            Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00033081
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Genotype: kuIs47 [AJM-1::GFP] Paper_evidence: WBPaper00033081
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000220 Paper_evidence: WBPaper00033081
        Curator_confirmed: WBPerson2021
        Remark: zmp-1 and lin-3 markers are expressed in the correct cell at the expected time in over 90% of the mutants Paper_evidence: WBPaper00033081
            Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00033081
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Genotype: syIs107[lin-3(delta-pes-10)::GFP], syIs49[zmp- 1::GFP] Paper_evidence: WBPaper00033081
              Curator_confirmed: WBPerson2021
      WBPhenotype:0000384 Paper_evidence: WBPaper00031828
        Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0003832 PATO:0000460 Paper_evidence: WBPaper00031828
                Curator_confirmed: WBPerson712
      WBPhenotype:0000679 Paper_evidence: WBPaper00035146
        Curator_confirmed: WBPerson712
        Remark: UNC-40::GFP is ventrally localized as in wild type animals. Paper_evidence: WBPaper00035146
            Curator_confirmed: WBPerson712
  Reference (13)
  Method: Substitution_allele