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WormBase Tree Display for Variation: WBVar00092034

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Name Class

WBVar00092034NamePublic_nameok754
Other_nameF42A10.2c.1:c.440_1240del
F42A10.2a.1:c.440_1240del
CE26892:p.His147_Ter414delinsPro
F42A10.2b.1:c.440_1240del
CE01293:p.His147_Ter414delinsPro
CE37913:p.His147_Ter414delinsPro
HGVSgCHROMOSOME_III:g.6160794_6161835del
Sequence_detailsSMapS_parentSequenceF42A10
Flanking_sequencesaaatctagtaaaaacgaattaattttcagcctctgttgagaatggaacgaaaagctcggg
Mapping_targetF42A10
Type_of_mutationDeletion
PCR_productok754_external
ok754_internal
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00035868
LaboratoryRB
PersonWBPerson46
KO_consortium_allele
StatusLive
AffectsGeneWBGene00003593
TranscriptF42A10.2c.1 (11)
F42A10.2b.1 (11)
F42A10.2a.1 (11)
InteractorWBInteraction000537328
WBInteraction000537329
WBInteraction000537330
WBInteraction000537331
IsolationMutagenUV/TMP
DescriptionPhenotypeWBPhenotype:0000059Curator_confirmedWBPerson712
RemarkThese animals also grew to be sterile adults, indicating that Pmyo-3::nfm-1(+)::gfp expression partially rescued the larval arrest of nfm-1(ok754)M+ animals.Curator_confirmedWBPerson712
WBPhenotype:0000469Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
RemarkIn nfm-1(ok754)M+, 2/20 QR.a/p daughters failed to migrate anteriorly and stayed near their birthplace, even after QL.a had migrated posteriorly (Figure 3, G and H).Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
Rescued_by_transgeneWBTransgene00023701
EQ_annotationsAnatomy_termWBbt:0004054PATO:0000460Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
WBbt:0003927PATO:0000460Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
WBPhenotype:0001140Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
Rescued_by_transgeneWBTransgene00023701
EQ_annotationsAnatomy_termWBbt:0003927PATO:0000460Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
WBbt:0004096PATO:0000460Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000594Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
RemarkNo defects were observed in the direction of protrusion. Despite reduced protrusions in nfm-1 mutants, the Q cells completed their anterior and posterior migrations before division (n > 20 for both ok754 and lq132).Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0008598PATO:0000460Paper_evidenceWBPaper00050480
Curator_confirmedWBPerson712
ReferenceWBPaper00050480
RemarkSequenced by the C. elegans Gene Knockout ConsortiumPaper_evidenceWBPaper00041807
MethodKO_consortium_allele