WormBase Tree Display for Variation: WBVar00091628

WBVar00091628 Evidence: Paper_evidence: WBPaper00006306
  Name: Public_name: ok330
    Other_name: F53A2.8c.1:c.1086_1425+107del
      F53A2.8a.1:c.1092_1431+107del
      F53A2.8b.1:c.1410_1749+107del
    HGVSg: CHROMOSOME_III:g.13353397_13354631del
  Sequence_details: SMap: S_parent: Sequence: F53A2
    Flanking_sequences: cccatactaccgtactattcacggatttca gtgcttgtgccgatttacgggcaattccaa
    Mapping_target: F53A2
    Type_of_mutation: Deletion
    PCR_product: OK330_external
      OK330_internal
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00035548
    Laboratory: RB
    Person: WBPerson46
    KO_consortium_allele
    Status: Live
  Affects: Gene: WBGene00003478
    Transcript: F53A2.8c.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F53A2.8c.1:c.1086_1425+107del
        cDNA_position: 1106-?
        CDS_position: 1086-?
        Protein_position: 362-?
        Intron_number: 5-7/9
        Exon_number: 5-7/10
      F53A2.8b.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F53A2.8b.1:c.1410_1749+107del
        cDNA_position: 1427-?
        CDS_position: 1410-?
        Protein_position: 470-?
        Intron_number: 5-7/9
        Exon_number: 5-7/10
      F53A2.8a.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: F53A2.8a.1:c.1092_1431+107del
        cDNA_position: 1112-?
        CDS_position: 1092-?
        Protein_position: 364-?
        Intron_number: 5-7/9
        Exon_number: 5-7/10
    Interactor: WBInteraction000521868
      WBInteraction000521869
      WBInteraction000521870
      WBInteraction000521871
      WBInteraction000521872
  Genetics: Mapping_data: In_multi_point: 4503
  Description: Phenotype_not_observed: WBPhenotype:0000590 Paper_evidence: WBPaper00035284
        Curator_confirmed: WBPerson2021
        Remark: The appearance of cell corpses was indistinguishable from that in wild-type embryos Paper_evidence: WBPaper00035284
            Curator_confirmed: WBPerson2021
      WBPhenotype:0000706 Paper_evidence: WBPaper00025094
        Curator_confirmed: WBPerson2021
        Remark: Mutations did not result in Glo phenotypes Paper_evidence: WBPaper00025094
            Curator_confirmed: WBPerson2021
        Variation_effect: Null: Paper_evidence: WBPaper00025094
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: Staining with LysoTracker Red and acridine orange Paper_evidence: WBPaper00025094
              Curator_confirmed: WBPerson2021
      WBPhenotype:0010004 Paper_evidence: WBPaper00031805
        Curator_confirmed: WBPerson2021
        Remark: Disruption of the FYVE-domain-containing proteins did not cause obvious defects in corpse removal in the germ line Paper_evidence: WBPaper00031805
            Curator_confirmed: WBPerson2021
  Reference: WBPaper00031805
    WBPaper00035284
    WBPaper00025094
  Remark: Sequenced by the C. elegans Gene Knockout Consortium Paper_evidence: WBPaper00041807
  Method: KO_consortium_allele