WormBase Tree Display for Variation: WBVar00088848

WBVar00088848 Evidence: Paper_evidence: WBPaper00003560
  Name: Public_name: md1401
    Other_name: CE24927:p.Ile133Val
      F27D9.1a.1:c.397A>G
    HGVSg: CHROMOSOME_X:g.7683493A>G
  Sequence_details: SMap: S_parent: Sequence: F27D9
    Flanking_sequences: cgtttcatcaaaactctgaaggagattaac tagctttcactccatacgaaagccaggtga
    Mapping_target: F27D9
    Type_of_mutation: Substitution: a g Paper_evidence: WBPaper00003560
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Laboratory: RM
    Status: Live
  Affects: Gene: WBGene00006757
    Transcript: F27D9.1a.1 (12)
  Genetics: Interpolated_map_position: X -1.35816
  Description: Phenotype: WBPhenotype:0000273 Paper_evidence: WBPaper00032271
        Curator_confirmed: WBPerson2021
        Remark: md1401 mutants moved slightly slower (30%) than the wild-type in solution Paper_evidence: WBPaper00032271
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Genotype: unc-18(e81) Paper_evidence: WBPaper00032271
              Curator_confirmed: WBPerson2021
      WBPhenotype:0001613 Paper_evidence: WBPaper00032271
        Curator_confirmed: WBPerson2021
        Remark: The effects of ethanol to depress behavioral activity was reduced for md1401 worms in comparison with Bristol N2 wild types Paper_evidence: WBPaper00032271
            Curator_confirmed: WBPerson2021
        Phenotype_assay: Treatment: 400mM EtOH Paper_evidence: WBPaper00032271
              Curator_confirmed: WBPerson2021
          Genotype: unc-18(e81) Paper_evidence: WBPaper00032271
              Curator_confirmed: WBPerson2021
  Disease_info: Models_disease: DOID:1574
    Models_disease_in_annotation: WBDOannot00000712
  Reference: WBPaper00032271
  Method: Substitution_allele