WormBase Tree Display for Variation: WBVar00087873

WBVar00087873 Name: Public_name: he141
    Other_name: C17G10.4h.1:c.742_1665+188del
      C17G10.4a.1:c.742_1624-272del
      C17G10.4c.1:c.742_1624-272del
      C17G10.4g.1:c.742_1665+188del
      C17G10.4e.1:c.742_1665+188del
      C17G10.4d.1:c.742_1624-272del
    HGVSg: CHROMOSOME_II:g.5591256_5592456del
  Sequence_details: SMap: S_parent: Sequence: C17G10
    Flanking_sequences: gtttcaacaattgttcggttgaatgcaaaa aaatatcgtgcccggtctcgacacgacaat
    Mapping_target: C17G10
    Type_of_mutation: Deletion
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00034606
    Laboratory: SV
    Status: Live
  Affects: Gene: WBGene00000383
    Transcript: C17G10.4c.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C17G10.4c.1:c.742_1624-272del
        cDNA_position: 796-?
        CDS_position: 742-?
        Protein_position: 248-?
        Intron_number: 5/7
        Exon_number: 5/8
      C17G10.4d.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C17G10.4d.1:c.742_1624-272del
        cDNA_position: 795-?
        CDS_position: 742-?
        Protein_position: 248-?
        Intron_number: 5/7
        Exon_number: 5/8
      C17G10.4a.1 VEP_consequence: splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C17G10.4a.1:c.742_1624-272del
        cDNA_position: 794-?
        CDS_position: 742-?
        Protein_position: 248-?
        Intron_number: 5/8
        Exon_number: 5/9
      C17G10.4h.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C17G10.4h.1:c.742_1665+188del
        cDNA_position: 796-?
        CDS_position: 742-?
        Protein_position: 248-?
        Intron_number: 5-6/8
        Exon_number: 5-6/9
      C17G10.4e.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C17G10.4e.1:c.742_1665+188del
        cDNA_position: 796-?
        CDS_position: 742-?
        Protein_position: 248-?
        Intron_number: 5-6/9
        Exon_number: 5-6/10
      C17G10.4g.1 VEP_consequence: splice_acceptor_variant,splice_donor_variant,coding_sequence_variant,intron_variant
        VEP_impact: HIGH
        HGVSc: C17G10.4g.1:c.742_1665+188del
        cDNA_position: 796-?
        CDS_position: 742-?
        Protein_position: 248-?
        Intron_number: 5-6/8
        Exon_number: 5-6/9
    Interactor: WBInteraction000500618
      WBInteraction000500619
      WBInteraction000500620
      WBInteraction000517292
  Genetics: Interpolated_map_position: II -1.07187
  Description: Phenotype: WBPhenotype:0000345 Paper_evidence: WBPaper00039834
        Curator_confirmed: WBPerson712
        Remark: Animals exhibit extra VPC cell divisions. Paper_evidence: WBPaper00039834
            Curator_confirmed: WBPerson712
        Phenotype_assay: Temperature: 15 Paper_evidence: WBPaper00039834
              Curator_confirmed: WBPerson712
      WBPhenotype:0000358 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Animals display extra cell divisions during post-embryonic development. In addition to extra VPCs, intestinal nuclei and hypodermal cells undergo extra divisions. Extra divisions were also observed in the ventral nerve cord Pn.p cells. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006898 PATO:0000460 Paper_evidence: WBPaper00024303
                Curator_confirmed: WBPerson712
            WBbt:0006899 PATO:0000460 Paper_evidence: WBPaper00024303
                Curator_confirmed: WBPerson712
            WBbt:0007846 PATO:0000460 Paper_evidence: WBPaper00024303
                Curator_confirmed: WBPerson712
            WBbt:0005792 PATO:0000460 Paper_evidence: WBPaper00024303
                Curator_confirmed: WBPerson712
            WBbt:0007809 PATO:0000460 Paper_evidence: WBPaper00024303
                Curator_confirmed: WBPerson712
    Phenotype_not_observed: WBPhenotype:0000050 Paper_evidence: WBPaper00039834
        Curator_confirmed: WBPerson712
        Remark: Animals do not exhibit any lethality at 15, 20, or 25 deg C. Paper_evidence: WBPaper00039834
            Curator_confirmed: WBPerson712
      WBPhenotype:0000062 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Animals are viable. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0000216 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Extra VPCs do not have an altered fate and where induced to adopt vulval fates in response to gain-of-function mutations of lin-12 and let-60. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0000519 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Animals are healthy. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0000648 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Despite extra Pn.p percursor cells, males mated efficiently. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0000688 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Animals are fertile. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0000749 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Animals complete embryogenesis without defects. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0001018 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Animals do not display any cytokinesis defects. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0001024 Paper_evidence: WBPaper00024303
        Curator_confirmed: WBPerson712
        Remark: Despite extra Pn.p percursor cells, males mated efficiently. Paper_evidence: WBPaper00024303
            Curator_confirmed: WBPerson712
        Recessive: Paper_evidence: WBPaper00024303
          Curator_confirmed: WBPerson712
      WBPhenotype:0001392 Paper_evidence: WBPaper00039834
        Curator_confirmed: WBPerson712
  Reference: WBPaper00024303
    WBPaper00039834
    WBPaper00044900
  Method: Deletion_allele