WormBase Tree Display for Variation: WBVar00000042

WBVar00000042 Evidence: Paper_evidence: WBPaper00031996
  Name: Public_name: ad601
    Other_name: B0365.3.1:c.1565G>A
      B0365.3.2:c.1565G>A
      CE07721:p.Gly522Glu
    HGVSg: CHROMOSOME_V:g.13128181C>T
  Sequence_details: SMap: S_parent: Sequence: B0365
    Flanking_sequences: acactgcctatcttgagttgggaggaatgg agaacgtgttctcggattctgtgacttcgt
    Mapping_target: B0365
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00031996
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00005489
    Laboratory: DA
    Status: Live
  Affects: Gene: WBGene00001137
    Transcript: B0365.3.2 (12)
      B0365.3.1 (12)
    Interactor: WBInteraction000503690
      WBInteraction000503691
      WBInteraction000541752
      WBInteraction000541753
  Genetics: Interpolated_map_position: V 4.9376
  Description: Phenotype (12)
    Phenotype_not_observed: WBPhenotype:0000655 Paper_evidence: WBPaper00031996
        Curator_confirmed: WBPerson712
        Remark: Animals responded like wild type to GABA agonist muscimol (data not shown) Paper_evidence: WBPaper00031996
            Curator_confirmed: WBPerson712
        Affected_by: Molecule: WBMol:00003906 Paper_evidence: WBPaper00031996
              Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0006804 PATO:0000460 Paper_evidence: WBPaper00031996
                Curator_confirmed: WBPerson712
        Phenotype_assay: Treatment: Animals were treated with muscimol. Paper_evidence: WBPaper00031996
              Curator_confirmed: WBPerson712
      WBPhenotype:0001321 Paper_evidence: WBPaper00031996
        Curator_confirmed: WBPerson712
        Remark: No gross differences were observed in the pan-neuronal or GABAergic pattern or expression levels of synaptic vesicle protein SNB-1::GFP compared to wild type. Paper_evidence: WBPaper00031996
            Curator_confirmed: WBPerson712
        EQ_annotations: Anatomy_term: WBbt:0005829 PATO:0000460 Paper_evidence: WBPaper00031996
                Curator_confirmed: WBPerson712
        Phenotype_assay: Genotype: jsIs1 (Psnb-1::SNB-1::GFP) or juIs1 (Punc-25::SNB-1::GFP) Paper_evidence: WBPaper00031996
              Curator_confirmed: WBPerson712
  Reference: WBPaper00015075
    WBPaper00031996
    WBPaper00001709
    WBPaper00003257
  Method: Substitution_allele