WormBase Tree Display for Variation: WBVar00143722
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| WBVar00143722 | Name | Public_name | e1072 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Other_name | e1072am | ||||||||
| Sequence_details | SeqStatus | Pending_curation | |||||||
| Variation_type | Allele | ||||||||
| Origin | Species | Caenorhabditis elegans | |||||||
| Strain | WBStrain00000019 | ||||||||
| WBStrain00000044 | |||||||||
| WBStrain00000140 | |||||||||
| WBStrain00000368 | |||||||||
| WBStrain00000369 | |||||||||
| WBStrain00000380 | |||||||||
| WBStrain00003963 | |||||||||
| WBStrain00003966 | |||||||||
| WBStrain00003967 | |||||||||
| WBStrain00003975 | |||||||||
| WBStrain00004240 | |||||||||
| WBStrain00004780 | |||||||||
| WBStrain00005540 | |||||||||
| WBStrain00005831 | |||||||||
| WBStrain00006216 | |||||||||
| WBStrain00006263 | |||||||||
| WBStrain00006331 | |||||||||
| WBStrain00006342 | |||||||||
| WBStrain00007122 | |||||||||
| WBStrain00007123 | |||||||||
| WBStrain00007910 | |||||||||
| WBStrain00008444 | |||||||||
| WBStrain00008446 | |||||||||
| WBStrain00008461 | |||||||||
| WBStrain00022563 | |||||||||
| WBStrain00022589 | |||||||||
| WBStrain00026525 | |||||||||
| WBStrain00027015 | |||||||||
| WBStrain00027016 | |||||||||
| WBStrain00027017 | |||||||||
| WBStrain00027018 | |||||||||
| WBStrain00027019 | |||||||||
| WBStrain00027020 | |||||||||
| WBStrain00027044 | |||||||||
| WBStrain00027080 | |||||||||
| WBStrain00027307 | |||||||||
| WBStrain00027364 | |||||||||
| WBStrain00027511 | |||||||||
| WBStrain00027512 | |||||||||
| WBStrain00027513 | |||||||||
| WBStrain00027514 | |||||||||
| WBStrain00027515 | |||||||||
| WBStrain00030687 | |||||||||
| WBStrain00030888 | |||||||||
| WBStrain00034397 | |||||||||
| WBStrain00034398 | |||||||||
| WBStrain00034653 | |||||||||
| WBStrain00057305 | |||||||||
| Laboratory | CB | ||||||||
| RAF | |||||||||
| Status | Live | ||||||||
| Affects | Gene | WBGene00006765 | |||||||
| Interactor | WBInteraction000556210 | ||||||||
| WBInteraction000556213 | |||||||||
| Genetics | Mapping_data | In_2_point (16) | |||||||
| In_multi_point (67) | |||||||||
| In_pos_neg_data | 745 | ||||||||
| 754 | |||||||||
| 763 | |||||||||
| 2516 | |||||||||
| 5849 | |||||||||
| 7288 | |||||||||
| 8083 | |||||||||
| 8095 | |||||||||
| 8103 | |||||||||
| 8110 | |||||||||
| Description | Phenotype | WBPhenotype:0000017 | Paper_evidence | WBPaper00004310 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | unc-29 mutants are strongly resistant to aldicarb | Paper_evidence | WBPaper00004310 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Affected_by | Molecule | WBMol:00003650 | Paper_evidence | WBPaper00004310 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000421 | Paper_evidence | WBPaper00000484 | |||||||
| WBPaper00004310 | |||||||||
| WBPaper00027611 | |||||||||
| Curator_confirmed (2) | |||||||||
| Remark | unc-29 mutants are strongly resistant to levamisole | Paper_evidence | WBPaper00004310 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Affected_by | Molecule | WBMol:00004019 | Paper_evidence | WBPaper00000484 | |||||
| WBPaper00004310 | |||||||||
| WBPaper00027611 | |||||||||
| Curator_confirmed (2) | |||||||||
| Phenotype_assay | Treatment | 1mM levamisole | Paper_evidence | WBPaper00000484 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000554 | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Mutants succumb to osmotic shock. | Paper_evidence | WBPaper00000484 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Phenotype_assay | Treatment | 10mM HEPES (pH 7.0), 0.25 per cent TWEEN 20. | Paper_evidence | WBPaper00000484 | |||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000643 | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | No backward motion in L1 larvae. Newly hatched larvae can barely move forward. Adults have a mild Unc defect where the mutants move forward in a slow decayed sine wave. | Paper_evidence | WBPaper00000484 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| EQ_annotations | Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00000484 | ||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00000484 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000782 | Paper_evidence | WBPaper00041265 | |||||||
| Curator_confirmed | WBPerson557 | ||||||||
| Remark | Adults have body-wall muscle with disorganized thick filaments. | Paper_evidence | WBPaper00041265 | ||||||
| Curator_confirmed | WBPerson557 | ||||||||
| Phenotype_assay | Treatment | Animals carried the GFP::MHC A transgene to mark thick filaments. | Paper_evidence | WBPaper00041265 | |||||
| Curator_confirmed | WBPerson557 | ||||||||
| WBPhenotype:0001315 | Paper_evidence | WBPaper00029130 | |||||||
| Curator_confirmed | WBPerson14391 | ||||||||
| Remark | No levamisole-AChR activity observed in isolated muscle cells | Paper_evidence | WBPaper00029130 | ||||||
| Curator_confirmed | WBPerson14391 | ||||||||
| WBPhenotype:0001645 | Paper_evidence | WBPaper00004117 | |||||||
| Curator_confirmed | WBPerson1754 | ||||||||
| Remark | Increased levels of protein degradation in muscle in response to starvation | Paper_evidence | WBPaper00004117 | ||||||
| Curator_confirmed | WBPerson1754 | ||||||||
| Phenotype_not_observed | WBPhenotype:0000315 | Paper_evidence | WBPaper00000484 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000478 | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Mutants tend to remain within the borders of bacterial lawns as does the wild-type. | Paper_evidence | WBPaper00000484 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0000964 | Paper_evidence | WBPaper00027611 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00000896 | Paper_evidence | WBPaper00027611 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001084 | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Attraction to sodium chloride is normal (See methods). | Paper_evidence | WBPaper00000484 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001232 | Paper_evidence | WBPaper00001861 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Remark | Male tail curling in reponse to serotonin is similar to WT | Paper_evidence | WBPaper00001861 | ||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Affected_by | Molecule | WBMol:00004929 | Paper_evidence | WBPaper00001861 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| EQ_annotations | Life_stage | WBls:0000056 | PATO:0000460 | Paper_evidence | WBPaper00001861 | ||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001414 | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Recessive | Paper_evidence | WBPaper00000484 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| WBPhenotype:0001426 | Paper_evidence | WBPaper00004883 | |||||||
| Curator_confirmed | WBPerson712 | ||||||||
| Phenotype_assay | Genotype | arIs37 | Paper_evidence | WBPaper00004883 | |||||
| Curator_confirmed | WBPerson712 | ||||||||
| WBPhenotype:0001645 | Paper_evidence | WBPaper00040284 | |||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| Remark | Table S2 | Paper_evidence | WBPaper00040284 | ||||||
| Curator_confirmed | WBPerson2987 | ||||||||
| WBPhenotype:0001853 | Paper_evidence | WBPaper00035150 | |||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Remark | Mutant response to AAD 1470 was comparable to that observed in wild-type | Paper_evidence | WBPaper00035150 | ||||||
| Curator_confirmed | WBPerson2021 | ||||||||
| Reference (22) | |||||||||
| Remark | |||||||||
| Method | Allele |
