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WormBase Tree Display for Variation: WBVar00143954

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Name Class

WBVar00143954EvidencePaper_evidenceWBPaper00025237
NamePublic_namee1377
Other_nameCE38955:p.Trp149Ter
F31F6.5.1:c.446G>A
HGVSgCHROMOSOME_X:g.14889428G>A
Sequence_detailsSMapS_parentSequenceF31F6
Flanking_sequencesattttcaggatctatgcctgagctacgattggtttgcggagccaacgagcatatccaaat
Mapping_targetF31F6
Type_of_mutationSubstitutionga
SeqStatusSequenced
Variation_typeAllele
OriginSpeciesCaenorhabditis elegans
StrainWBStrain00004313
WBStrain00004378
LaboratoryCB
StatusLive
Affects (3)
GeneticsInterpolated_map_positionX21.4994
Mapping_dataIn_2_point283
419
420
421
In_multi_point649
In_pos_neg_data2161
2169
2228
DescriptionPhenotypeWBPhenotype:0000013Paper_evidenceWBPaper00000316
WBPaper00000504
WBPaper00000503
Person_evidenceWBPerson261
Curator_confirmedWBPerson712
RemarkWill not form Dauers upon starved plates or in liquid culture.Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
defective dauer formationPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000150Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0000247Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
Remark1/30 L2 larva, 3/30 adults move to within 1 cm of the center of a 50mM Na+ gradient in an orientation assay. Whereas 25/28 L2 N2 larva and 28/30 N2 adults move to within 1 cm of the center in the same assay.Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000027PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBls:0000041PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0000249Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkdefective osmotic avoidancePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000254Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0000256Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
RemarkAmphid sheath cells are enlarged and there is an accumulation of large vesicles.Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000027PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBls:0000041PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0000300Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
RemarkVesicles accumulate in the sheath cells.Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000027PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBls:0000041PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0000604Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkabnormal sensory anatomy especially amphidial sheath cells (resembles Che-14)Person_evidenceWBPerson261
Curator_confirmedWBPerson712
EQ_annotationsAnatomy_termWBbt:0006754PATO:0000460Person_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0000637Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkDefective response to dauer inducing conditions as assayed by SDS resistance of animals from a starved, crowded plate.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0000663Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0000843Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
RemarkMale mating efficiency is reduced to 30% that of WT.Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0001084Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkDefective response to dilute NaCl gradient.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0001414Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkpoor male matingPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0001418Paper_evidenceWBPaper00044578
Curator_confirmedWBPerson12259
RemarkFigure 5BPaper_evidenceWBPaper00044578
Curator_confirmedWBPerson12259
WBPhenotype:0001434Person_evidenceWBPerson261
Curator_confirmedWBPerson712
Remarkabnormal chemotaxisPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
WBPhenotype:0001528Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkSocket and sheath channels do not join.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0001533Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
RemarkLateral outer labial neurons were missing in L2 and OL tips were missing in adultsPaper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000027PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBls:0000041PATO:0000460Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0001692Paper_evidenceWBPaper00002589
Curator_confirmedWBPerson712
RemarkAnimals did not display the L2 M37 epitope to the same extent as wildtype when grown in the presence of pheromone, e.g. animals were ILD defective.Paper_evidenceWBPaper00002589
Curator_confirmedWBPerson712
WBPhenotype:0002535Paper_evidenceWBPaper00002087
WBPaper00000932
Person_evidenceWBPerson261
Curator_confirmedWBPerson48
WBPerson712
RemarkDefects in dye filling.Paper_evidenceWBPaper00002087
Curator_confirmedWBPerson48
FITC rarely if ever stains amphids or phasmids.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
Dyf, no FITC uptake by amphids or phasmidsPerson_evidenceWBPerson261
Curator_confirmedWBPerson712
RecessivePaper_evidenceWBPaper00002087
Curator_confirmedWBPerson48
Ease_of_scoringES1_Very_hard_to_scorePerson_evidenceWBPerson261
Curator_confirmedWBPerson712
Phenotype_not_observedWBPhenotype:0000315Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0000398Paper_evidenceWBPaper00000503
Curator_confirmedWBPerson712
WBPhenotype:0000478Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0000505Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkNo FITC staining of ray sensilla.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0000843Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkMating efficiency 4; 30-100% of WT mating efficiency.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
EQ_annotationsLife_stageWBls:0000056PATO:0000460Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
Phenotype_assayGenotypehim-5(e1490)Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0001438Paper_evidenceWBPaper00001786
Curator_confirmedWBPerson2021
EQ_annotationsLife_stageWBls:0000041PATO:0000460Paper_evidenceWBPaper00001786
Curator_confirmedWBPerson2021
WBPhenotype:0001530Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkNo FITC staining of CEP.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
WBPhenotype:0001535Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
RemarkNo FITC staining of ADE or PDE.Paper_evidenceWBPaper00000932
Curator_confirmedWBPerson712
Reference (17)
MethodSubstitution_allele