WormBase Tree Display for Variation: WBVar00240985
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WBVar00240985 | Name | Public_name | q20 | ||||||
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Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Strain | WBStrain00004583 | ||||||||
WBStrain00022523 | |||||||||
WBStrain00022525 | |||||||||
Laboratory | JK | ||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00001413 | |||||||
Interactor | WBInteraction000050596 | ||||||||
WBInteraction000503024 | |||||||||
WBInteraction000524787 | |||||||||
WBInteraction000556052 | |||||||||
WBInteraction000556054 | |||||||||
WBInteraction000557074 | |||||||||
WBInteraction000557077 | |||||||||
WBInteraction000558239 | |||||||||
Genetics | Mapping_data | In_multi_point | 1911 | ||||||
Description | Phenotype | WBPhenotype:0000038 | Paper_evidence | WBPaper00050044 | |||||
Curator_confirmed | WBPerson17144 | ||||||||
Remark | Increase rupture post-reproductively | Paper_evidence | WBPaper00050044 | ||||||
Curator_confirmed | WBPerson17144 | ||||||||
WBPhenotype:0000416 | Paper_evidence | WBPaper00039871 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Yolk protein levels were elevated in animals. | Paper_evidence | WBPaper00039871 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000683 | Paper_evidence | WBPaper00028730 | |||||||
Person_evidence | WBPerson261 | ||||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | At 25C XX germline makes only sperm, at 15C XX germline makes oocytes and excess sperm. | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Semi_dominant | Person_evidence | WBPerson261 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Variation_effect | Hypermorph_gain_of_function | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Temperature_sensitive | Heat_sensitive | 25 | Person_evidence | WBPerson261 | |||||
Curator_confirmed | WBPerson712 | ||||||||
Ease_of_scoring | ES3_Easy_to_score | Person_evidence | WBPerson261 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001779 | Paper_evidence | WBPaper00035664 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | miRNA 35-41 expression is disrupted | Paper_evidence | WBPaper00035664 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Temperature_sensitive | Heat_sensitive | Paper_evidence | WBPaper00035664 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001823 | Paper_evidence | WBPaper00028527 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Male sperm failed to accumulate in the spermatheca | Paper_evidence | WBPaper00028527 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
EQ_annotations | Life_stage | WBls:0000057 | PATO:0000460 | Paper_evidence | WBPaper00028527 | ||||
Curator_confirmed | WBPerson2021 | ||||||||
Phenotype_assay | Treatment | Wild-type males labelled with MitoTracker were mated to non-labelled mutant hermaphrodites | Paper_evidence | WBPaper00028527 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001824 | Paper_evidence | WBPaper00035521 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | N2 prophase was completed between 16-21 hr; similarly, meiotic prophase kinetics of fem-3(gf) XX animals (25C) was completed by 21 hr. | Paper_evidence | WBPaper00035521 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_not_observed | WBPhenotype:0000113 | Paper_evidence | WBPaper00031903 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Expression of 21 U RNAs was normal. | Paper_evidence | WBPaper00031903 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Variation_effect | Hypermorph_gain_of_function | Paper_evidence | WBPaper00031903 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000038 | PATO:0000460 | Paper_evidence | WBPaper00031903 | ||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Treatment | Samples were enriched for RNAs <200 bp and used in northern analysis to examine the expression profile of the 21U-RNA 21ur-1 as | Paper_evidence | WBPaper00031903 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0000114 | Paper_evidence | WBPaper00034714 | |||||||
WBPaper00039871 | |||||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPerson712 | |||||||||
Remark | Expression of elt-1 was detectable during spermatogenesis in fem-3 adults beginning at pachytene and extending through the formation of haploid spermatids , the same pattern that was observed in wildtype L4 animals | Paper_evidence | WBPaper00034714 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
vit-2 and -5 mRNA levels were normal. The levels of sod-3 mRNA were also roughly normal. | Paper_evidence | WBPaper00039871 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Variation_effect | Hypermorph_gain_of_function | Paper_evidence | WBPaper00034714 | ||||||
WBPaper00039871 | |||||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPerson712 | |||||||||
Temperature_sensitive | Heat_sensitive | Paper_evidence | WBPaper00034714 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Phenotype_assay | Treatment | In situ hybridization with elt-1 antisense probe | Paper_evidence | WBPaper00034714 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001182 | Paper_evidence | WBPaper00032310 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | fem-3(q20ts) mutants exhibited normal fat content at the nonpermissive temperature, compared to wild type controls, as determined by Nile Red staining (Figure 2A-D) | Paper_evidence | WBPaper00032310 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0001410 | Paper_evidence | WBPaper00040337 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Antibodies that recognize the nearly identical GSP-3 and GSP-4 (GSP-3/4) proteins were used to show that, similar to the sperm-specific MSP protein, GSP-3/4 are expressed only in sperm-producing fem-3(q20gf) but not oocyte-producing fem-1(hc17lf) mutant hermaphrodites. | Paper_evidence | WBPaper00040337 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Reference (17) | |||||||||
Method | Allele |