WormBase Tree Display for Variation: WBVar00143722
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WBVar00143722 | Name | Public_name | e1072 | ||||||
---|---|---|---|---|---|---|---|---|---|
Other_name | e1072am | ||||||||
Sequence_details | SeqStatus | Pending_curation | |||||||
Variation_type | Allele | ||||||||
Origin | Species | Caenorhabditis elegans | |||||||
Strain (48) | |||||||||
Laboratory | CB | ||||||||
RAF | |||||||||
Status | Live | ||||||||
Affects | Gene | WBGene00006765 | |||||||
Interactor | WBInteraction000556210 | ||||||||
WBInteraction000556213 | |||||||||
Genetics | Mapping_data | In_2_point (16) | |||||||
In_multi_point (67) | |||||||||
In_pos_neg_data | 745 | ||||||||
754 | |||||||||
763 | |||||||||
2516 | |||||||||
5849 | |||||||||
7288 | |||||||||
8083 | |||||||||
8095 | |||||||||
8103 | |||||||||
8110 | |||||||||
Description | Phenotype | WBPhenotype:0000017 | Paper_evidence | WBPaper00004310 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | unc-29 mutants are strongly resistant to aldicarb | Paper_evidence | WBPaper00004310 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Affected_by | Molecule | WBMol:00003650 | Paper_evidence | WBPaper00004310 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000421 | Paper_evidence | WBPaper00000484 | |||||||
WBPaper00004310 | |||||||||
WBPaper00027611 | |||||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPerson712 | |||||||||
Remark | unc-29 mutants are strongly resistant to levamisole | Paper_evidence | WBPaper00004310 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Recessive | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Affected_by | Molecule | WBMol:00004019 | Paper_evidence | WBPaper00000484 | |||||
WBPaper00004310 | |||||||||
WBPaper00027611 | |||||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPerson712 | |||||||||
Phenotype_assay | Treatment | 1mM levamisole | Paper_evidence | WBPaper00000484 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000554 | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Mutants succumb to osmotic shock. | Paper_evidence | WBPaper00000484 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Recessive | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Phenotype_assay | Treatment | 10mM HEPES (pH 7.0), 0.25 per cent TWEEN 20. | Paper_evidence | WBPaper00000484 | |||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000643 | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | No backward motion in L1 larvae. Newly hatched larvae can barely move forward. Adults have a mild Unc defect where the mutants move forward in a slow decayed sine wave. | Paper_evidence | WBPaper00000484 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Recessive | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
EQ_annotations | Life_stage | WBls:0000024 | PATO:0000460 | Paper_evidence | WBPaper00000484 | ||||
Curator_confirmed | WBPerson2021 | ||||||||
WBls:0000041 | PATO:0000460 | Paper_evidence | WBPaper00000484 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000782 | Paper_evidence | WBPaper00041265 | |||||||
Curator_confirmed | WBPerson557 | ||||||||
Remark | Adults have body-wall muscle with disorganized thick filaments. | Paper_evidence | WBPaper00041265 | ||||||
Curator_confirmed | WBPerson557 | ||||||||
Phenotype_assay | Treatment | Animals carried the GFP::MHC A transgene to mark thick filaments. | Paper_evidence | WBPaper00041265 | |||||
Curator_confirmed | WBPerson557 | ||||||||
WBPhenotype:0001315 | Paper_evidence | WBPaper00029130 | |||||||
Curator_confirmed | WBPerson14391 | ||||||||
Remark | No levamisole-AChR activity observed in isolated muscle cells | Paper_evidence | WBPaper00029130 | ||||||
Curator_confirmed | WBPerson14391 | ||||||||
WBPhenotype:0001645 | Paper_evidence | WBPaper00004117 | |||||||
Curator_confirmed | WBPerson1754 | ||||||||
Remark | Increased levels of protein degradation in muscle in response to starvation | Paper_evidence | WBPaper00004117 | ||||||
Curator_confirmed | WBPerson1754 | ||||||||
Phenotype_not_observed | WBPhenotype:0000315 | Paper_evidence | WBPaper00000484 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Recessive | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000478 | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Mutants tend to remain within the borders of bacterial lawns as does the wild-type. | Paper_evidence | WBPaper00000484 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Recessive | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0000964 | Paper_evidence | WBPaper00027611 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00000896 | Paper_evidence | WBPaper00027611 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001084 | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Attraction to sodium chloride is normal (See methods). | Paper_evidence | WBPaper00000484 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Recessive | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001232 | Paper_evidence | WBPaper00001861 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Remark | Male tail curling in reponse to serotonin is similar to WT | Paper_evidence | WBPaper00001861 | ||||||
Curator_confirmed | WBPerson712 | ||||||||
Affected_by | Molecule | WBMol:00004929 | Paper_evidence | WBPaper00001861 | |||||
Curator_confirmed | WBPerson712 | ||||||||
EQ_annotations | Life_stage | WBls:0000056 | PATO:0000460 | Paper_evidence | WBPaper00001861 | ||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001414 | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Recessive | Paper_evidence | WBPaper00000484 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
WBPhenotype:0001426 | Paper_evidence | WBPaper00004883 | |||||||
Curator_confirmed | WBPerson712 | ||||||||
Phenotype_assay | Genotype | arIs37 | Paper_evidence | WBPaper00004883 | |||||
Curator_confirmed | WBPerson712 | ||||||||
WBPhenotype:0001645 | Paper_evidence | WBPaper00040284 | |||||||
Curator_confirmed | WBPerson2987 | ||||||||
Remark | Table S2 | Paper_evidence | WBPaper00040284 | ||||||
Curator_confirmed | WBPerson2987 | ||||||||
WBPhenotype:0001853 | Paper_evidence | WBPaper00035150 | |||||||
Curator_confirmed | WBPerson2021 | ||||||||
Remark | Mutant response to AAD 1470 was comparable to that observed in wild-type | Paper_evidence | WBPaper00035150 | ||||||
Curator_confirmed | WBPerson2021 | ||||||||
Reference (22) | |||||||||
Remark | |||||||||
Method | Allele |