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WormBase Tree Display for Transgene: WBTransgene00015193

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Name Class

WBTransgene00015193Public_namexqIs93
Summary[tdp-1p::TDP-1::GFP]
ConstructionConstructWBCnstr00014790
Integration_methodUV
Genetic_informationIntegrated
PhenotypeWBPhenotype:0001171Paper_evidenceWBPaper00041295
Curator_confirmedWBPerson712
RemarkOverexpression of TDP-1 fused to GFP from the endogenous tdp-1 promoter (tdp-1p::TDP-1::GFP) greatly reduced lifespan compared to wild type N2 worms and tdp-1 deletion mutants at 20 deg C. TDP-1::GFP transgenics showed a further decrease in mean and maximum lifespan when grown at 25 deg C compared to N2 worms.Paper_evidenceWBPaper00041295
Curator_confirmedWBPerson712
Caused_by_geneWBGene00006514Paper_evidenceWBPaper00041295
Curator_confirmedWBPerson712
Used_forExpr_patternExpr10097
Marker_forosmotic stress
oxidative stress
UPR(er)
InteractorWBInteraction000518826
WBInteraction000518827
Associated_withStrainWBStrain00046779
ReferenceWBPaper00041295
SpeciesCaenorhabditis elegans