WormBase Tree Display for Transgene: WBTransgene00015193
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WBTransgene00015193 | Public_name | xqIs93 | |||||
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Summary | [tdp-1p::TDP-1::GFP] | ||||||
Construction | Construct | WBCnstr00014790 | |||||
Integration_method | UV | ||||||
Genetic_information | Integrated | ||||||
Phenotype | WBPhenotype:0001171 | Paper_evidence | WBPaper00041295 | ||||
Curator_confirmed | WBPerson712 | ||||||
Remark | Overexpression of TDP-1 fused to GFP from the endogenous tdp-1 promoter (tdp-1p::TDP-1::GFP) greatly reduced lifespan compared to wild type N2 worms and tdp-1 deletion mutants at 20 deg C. TDP-1::GFP transgenics showed a further decrease in mean and maximum lifespan when grown at 25 deg C compared to N2 worms. | Paper_evidence | WBPaper00041295 | ||||
Curator_confirmed | WBPerson712 | ||||||
Caused_by_gene | WBGene00006514 | Paper_evidence | WBPaper00041295 | ||||
Curator_confirmed | WBPerson712 | ||||||
Used_for | Expr_pattern | Expr10097 | |||||
Marker_for | osmotic stress | ||||||
oxidative stress | |||||||
UPR(er) | |||||||
Interactor | WBInteraction000518826 | ||||||
WBInteraction000518827 | |||||||
Associated_with | Strain | WBStrain00046779 | |||||
Reference | WBPaper00041295 | ||||||
Species | Caenorhabditis elegans |