WormBase Tree Display for Strain: WBStrain00055594
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| WBStrain00055594 | Genotype | unc-73(az63) dxbp-1(az52) I; smg-4(az152) V. | ||
|---|---|---|---|---|
| Public_name | SZ355 | |||
| Contains | Gene | WBGene00004882 | ||
| WBGene00006805 | ||||
| WBGene00013128 | ||||
| Variation | WBVar02157568 | |||
| WBVar02157567 | ||||
| WBVar02157565 | ||||
| Properties | Outcrossed | x2 | ||
| Mutagen | CRISPR_Cas9 | |||
| CGC_received | 23 Aug 2023 00:00:00 | |||
| Location | CGC | |||
| Made_by | WBPerson713 | |||
| Remark | az52 is a CRISPR-engineered M107I missense allele of dxbp-1. az52 has no phenotype on its own, but suppresses unc-73(e936) and unc-73(az63) by promoting use of a cryptic splice site for an intron beginning with UU. smg-4(az152) provides an NMD deficient background allowing identification of out-of-frame mis-splicing in an RNA-seq experiment. Reference: Suzuki JMNGL, et al. PLoS Genet. 2022 Feb 10;18(2):e1010028. doi: 10.1371/journal.pgen.1010028. PMID: 35143478. | Inferred_automatically | From CGC strain data | |
| Species | Caenorhabditis elegans |
