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WormBase Tree Display for RNAi: WBRNAi00110668

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Name Class

WBRNAi00110668HomolHomol_homolF41H10:RNAi
Sequence_infoPCR_productsjj_F41H10.7
ExperimentTreatmentAnimals were subjected to elo-5 RNAi at later larval stages (L2-L4) and phenotypes monitored.
Delivered_byBacterial_feeding
InhibitsPredicted_geneF41H10.7Inferred_automaticallyRNAi_primary
GeneWBGene00001243Inferred_automaticallyRNAi_primary
TranscriptF41H10.7.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00024532
PhenotypeWBPhenotype:0001958RemarkAnimals were subjected to elo-5 RNAi at later larval stages (L2-L4). The growing worms became progressively sick. The gonads appeared normal at the L4 and early adult stages, but after fertilization of one to ten oocytes, oogenesis became impaired. Gonad degeneration began with a pronounced vacuolization in the midsection of the gonad followed by the appearance of disorganized clumps of nuclei in the proximal part. An egg-laying defect became apparent and only a few progeny arose from these worms, which then arrested at L1.
RemarkExact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
MethodRNAi