WormBase Tree Display for RNAi: WBRNAi00092400
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| WBRNAi00092400 | Homol | Homol_homol | T19E7:RNAi | ||
|---|---|---|---|---|---|
| Sequence_info | PCR_product | sjj_T19E7.2 | |||
| Experiment | Laboratory | RJ | |||
| Date | 20 Oct 2012 00:00:00 | ||||
| Genotype | Pdat-1::GFP; rrf-3(pk1426) | ||||
| Treatment | L1-staged worms were exposed to 100 micromolar AlCl3 (Aluminum Chloride) for 30 minutes and then allowed to recover on fresh RNAi plates for 72 hours, and dopamine neuronal death was evaluated. | ||||
| Delivered_by | Bacterial_feeding | ||||
| Inhibits | Predicted_gene | T19E7.2c | Inferred_automatically | RNAi_primary | |
| T19E7.2a | Inferred_automatically | RNAi_primary | |||
| T19E7.2b | Inferred_automatically | RNAi_primary | |||
| T19E7.2d | Inferred_automatically | RNAi_primary | |||
| Gene | WBGene00004804 | Inferred_automatically | RNAi_primary | ||
| Transcript | T19E7.2d.1 | Inferred_automatically | RNAi_primary | ||
| T19E7.2a.1 | Inferred_automatically | RNAi_primary | |||
| T19E7.2c.1 | Inferred_automatically | RNAi_primary | |||
| T19E7.2b.1 | Inferred_automatically | RNAi_primary | |||
| Species | Caenorhabditis elegans | ||||
| Interaction | WBInteraction000520190 | ||||
| Reference | WBPaper00041701 | ||||
| Phenotype | WBPhenotype:0000591 | Remark | skn-1 RNAi slightly (but significantly) enhanced the dopaminergic neuron degeneration induced by the presence of 100 micromolar Aluminum (Al3+), implicating SKN-1 in a neuroprotective role in Aluminum-induced dopaminergic neuron degeneration. | ||
| Affected_by | Molecule | WBMol:00002994 | |||
| WBPhenotype:0000636 | Remark | skn-1 RNAi slightly (but significantly) enhanced the dopaminergic neuron degeneration induced by the presence of 100 micromolar Aluminum (Al3+), implicating SKN-1 in a neuroprotective role in Aluminum-induced dopaminergic neuron degeneration. | |||
| Affected_by | Molecule | WBMol:00002994 | |||
| Remark | (Figure 6a) skn-1 RNAi | ||||
| Method | RNAi |
