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WormBase Tree Display for RNAi: WBRNAi00078433

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Name Class

WBRNAi00078433HomolHomol_homolC38C10:RNAi
Sequence_infoDNA_textggagcatccacccacgtcgaaatgctgtgttcaactatctctcacttataacaacacatcgaccaagaagctggcgccggcgacgaaagtggatcaaccattgcagaatattattttcaatgtatggaagactgttattttcttgcctggctctcttcaaaaaattcaaattttcaggttatcgtcagtcaaagtcgtacttcagaatcatttagtgttcttcgatttatctatagaattaaagagtaagttcttgtactttaaagtggagctgcgagtgaattttgcttcaaaattaccaaaatagcagggggaaaaatcgaaaatgaataataatccaacttctaaagagaattttcaatttttccaaatttccacttttgaattcgttccaaactgaaaacggaaagaccaatcagcgatctgccccgcctacttacaccgtctgattggttgaagaatgggcggagcgaatcgctgattgatattgcagttctcattttgttcagacagagagagctttctcgattttctttttgttgctttgtggtatttctgaatttcagattattttggatattttaacgcaaaatcaccattcaataaatttactttttcaaaggacctcccatttttaattaaatcaaatttcagaaactttgtggttgttccatcagctaatgaaaagaacaaacaaatggcagatgaagtaaacgctgaaacaaagacttctgggggaaatccaatttggaatctggtgcgtctcgttatggatcgattcaactcgggcgactggaatcctggaaaccgaga
ExperimentLaboratoryLD
Date20 Jun 2002 00:00:00
Delivered_byInjection
InhibitsPredicted_geneC38C10.5aInferred_automaticallyRNAi_primary
C38C10.5bInferred_automaticallyRNAi_primary
GeneWBGene00004343Inferred_automaticallyRNAi_primary
TranscriptC38C10.5a.1Inferred_automaticallyRNAi_primary
C38C10.5b.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00005433
PhenotypeWBPhenotype:0000113RemarkRGR-1 is required broadly for early embryonic transcription. Authors used various transgenes to show this. They also showed that maternal PIE-1::GFP expression and localization patterns appeared normal at every stage, therefore RGR-1 does not detectably affect maternal mRNA stores but may broadly impair new mRNA transcription.
WBPhenotype:0000354RemarkEmbryos arrest development after forming approximately100 cells that lack any signs of differentiation.
WBPhenotype:0000867RemarkEmbryos arrest development after forming approximately100 cells that lack any signs of differentiation.
WBPhenotype:0001351RemarkPhosphorylation of Pol II CTD Ser-2 and Ser-5 is undetectable. Rgr-1 plays a generally critical role early during the transcription cycle prior to phosphorylation of the Pol II CTD.
MethodRNAi