WormBase Tree Display for RNAi: WBRNAi00078392
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WBRNAi00078392 | Homol | Homol_homol | R13A1:RNAi | ||
---|---|---|---|---|---|
Sequence_info | PCR_product | sjj_R13A1.8 | |||
Experiment | Laboratory | CK | |||
Date | 16 Mar 2006 00:00:00 | ||||
Genotype | aex-3::tau (FTDP-17 mutant human tau); myo-2::GFP | ||||
Treatment | The FTDP-17 mutant human tau used in the transgene for this experiment contains a V337M change with its expression driven by the pan-neuronal promoter aex-3. The animals containing this transgene have what is called a tau-induced Unc phenotype. | ||||
Delivered_by | Bacterial_feeding | ||||
Inhibits | Predicted_gene | R13A1.8 | Inferred_automatically | RNAi_primary | |
Gene | WBGene00006504 | Inferred_automatically | RNAi_primary | ||
WBGene00020045 | Inferred_automatically | RNAi_primary | |||
Transcript | R13A1.2c.1 | Inferred_automatically | RNAi_primary | ||
R13A1.2a.1 | Inferred_automatically | RNAi_primary | |||
R13A1.8.1 | Inferred_automatically | RNAi_primary | |||
Species | Caenorhabditis elegans | ||||
Interaction | WBInteraction000050742 | ||||
Reference | WBPaper00027214 | ||||
Phenotype | WBPhenotype:0000643 | Remark | This RNAi enhanced the tau-induced uncoordinated (Unc) phenotype (caused by the expression of mutant human tau -FTDP-17) as well as the Unc phenotype some/all of the four Unc lines tested (unc-3, unc-76, unc-78 and unc-87). | ||
Method | RNAi |