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WormBase Tree Display for RNAi: WBRNAi00078392

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Name Class

WBRNAi00078392HomolHomol_homolR13A1:RNAi
Sequence_infoPCR_productsjj_R13A1.8
ExperimentLaboratoryCK
Date16 Mar 2006 00:00:00
Genotypeaex-3::tau (FTDP-17 mutant human tau); myo-2::GFP
TreatmentThe FTDP-17 mutant human tau used in the transgene for this experiment contains a V337M change with its expression driven by the pan-neuronal promoter aex-3. The animals containing this transgene have what is called a tau-induced Unc phenotype.
Delivered_byBacterial_feeding
InhibitsPredicted_geneR13A1.8Inferred_automaticallyRNAi_primary
GeneWBGene00006504Inferred_automaticallyRNAi_primary
WBGene00020045Inferred_automaticallyRNAi_primary
TranscriptR13A1.2c.1Inferred_automaticallyRNAi_primary
R13A1.2a.1Inferred_automaticallyRNAi_primary
R13A1.8.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000050742
ReferenceWBPaper00027214
PhenotypeWBPhenotype:0000643RemarkThis RNAi enhanced the tau-induced uncoordinated (Unc) phenotype (caused by the expression of mutant human tau -FTDP-17) as well as the Unc phenotype some/all of the four Unc lines tested (unc-3, unc-76, unc-78 and unc-87).
MethodRNAi