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WormBase Tree Display for RNAi: WBRNAi00078380

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Name Class

WBRNAi00078380HomolHomol_homolC14C11:RNAi
ZC317:RNAi
Sequence_infoPCR_productsjj_C14C11.6
ExperimentLaboratoryCK
Date16 Mar 2006 00:00:00
Genotypeaex-3::tau (FTDP-17 mutant human tau); myo-2::GFP
TreatmentThe FTDP-17 mutant human tau used in the transgene for this experiment contains a V337M change with its expression driven by the pan-neuronal promoter aex-3. The animals containing this transgene have what is called a tau-induced Unc phenotype.
Delivered_byBacterial_feeding
InhibitsPredicted_geneC14C11.6Inferred_automaticallyRNAi_primary
GeneWBGene00003507Inferred_automaticallyRNAi_primary
TranscriptC14C11.6.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
InteractionWBInteraction000050730
ReferenceWBPaper00027214
PhenotypeWBPhenotype:0000643RemarkThis RNAi enhanced the tau-induced uncoordinated (Unc) phenotype (caused by the expression of mutant human tau -FTDP-17) as well as the Unc phenotype some/all of the four Unc lines tested (unc-3, unc-76, unc-78 and unc-87).
MethodRNAi