WormBase Tree Display for Picture: WBPicture0000014042
expand all nodes | collapse all nodes | view schema
| WBPicture0000014042 | Description | Figure S1. mak-2 encodes a C. elegans MAPKAP kinase expressed in neurons and localized to synapses independent of its NLS and NES(A) The rpm-1 suppressor ju637 was mapped to the left arm of chromosome IV and linked to SNP Y55F3BR[7]. tm2927 and ok2394 are deletion alleles of mak2.(B) mak-2 promoter (3,448 bp) driven GFP shows broad expression in the nervous system, muscle and other tissues. (C) mak-2 expression constructs. (D) Deleting the NES or NLS of MAK-2 affects its nuclear localization but not its synaptic localization in PLM touch neurons. (E) Phosphomimetic MAK-2(EE) and nonphosphorylatable MAK-2(AA) are localized to motor neuron synapses (left panels) and the cell body (right panels). Note that expression of MAK-2(EE) causes abnormal puncta of SNB-1::GFP. Scale bars, 10 um. | |||
|---|---|---|---|---|---|
| Name | FigS1.jpg | ||||
| Depict | Expr_pattern | Expr12815 | |||
| Anatomy | WBbt:0005735 | ||||
| Acknowledgment | Template | Reprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>. | |||
| Publication_year | 2009 | ||||
| Article_URL | DOI | id | 10.1016/j.cell.2009.06.023 | ||
| Journal_URL | Cell | ||||
| Publisher_URL | Elsevier | ||||
| Reference | WBPaper00035181 |
