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| WBPicture0000013952 | Description | FIGURE 4: Localization of MAK-1 in wild type and in mak-1 and unc-22 mutants. (A) Portion of an adult body wall muscle cell from wild type and each of the mak-1 mutants immunostained with the anti-C-terminal MAK-1 antibody and costained with anti-PAT-6 (alpha-parvin), which marks M-lines (denoted by an arrow) and dense bodies (denoted by an arrow head). Anti-MAK-1 localizes between and around dense bodies (top) in striated muscle cells. This localization was not detected in mak-1 mutant animals (middle and bottom). (B) Portion of a wild-type body wall muscle cell immunostained with anti-MAK-1 and anti-MHC B. Anti-MAK-1 partially colocalizes with anti-MHC B at the outer edges of A-bands. (C) Portion of an adult body wall muscle cell from two unc-22 mutant alleles, e105 and e66, immunostained with anti-MAK-1 and anti-PAT-6. The localization of MAK-1 is not affected by the presence of a mutant form of UNC-22 (twitchin). Scale bars, 10 um. | |||
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| Name | F4.large.jpg | ||||
| Depict | Expr_pattern | Expr12281 | |||
| Anatomy | WBbt:0006804 | ||||
| Cellular_component | GO:0031672 | ||||
| Acknowledgment | Template | WormBase thanks <Journal_URL> for permission to reproduce figures from this article <Article_URL>. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>. | |||
| Publication_year | 2015 | ||||
| Article_URL | DOI | id | 10.1091/mbc.E14-05-1009 | ||
| Journal_URL | MolecularBiologyoftheCell | ||||
| Publisher_URL | TheAmericanSocietyForCellBiology | ||||
| Reference | WBPaper00046636 |
