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WBPicture0000013637DescriptionFigure 1. The role of daf-2 in axonal regeneration. (A) Image and schematic of successful axonal fusion in a posterior lateral microtubule (PLM) neuron 24 h post-axotomy. Closed arrowhead shows cut site, open arrowhead shows fusion site. The posterior ventral microtubule (PVM) neuron is also visible in this image. Scale bar represents 25&micro;m. (B) Quantification of the average length of regrowth, (C) level of reconnection, (D) average length of retraction, and (E) average number of branches in daf-2(e1370); zdIs5 animals relative to wild-type (WT, zdIs5) across different ages. Dashed line designates a value of 1 (no change compared to WT). L4 = larval stage 4; A1 = one-day-old adult. P values from t test: * < 0.05, ** < 0.01, *** < 0.001; n values within each bar.
Nameabay1.jpg
SpeciesCaenorhabditis elegans
AcknowledgmentTemplateReprinted from <Journal_URL>
Publication_year2017
Article_URLDOIid10.17912/W2XD3R
Journal_URLmicroPublicationBiology
Publisher_URLMicropublication
ReferenceWBPaper00053569