WormBase Tree Display for Picture: WBPicture0000012556

WBPicture0000012556 Description: Figure 1. hlh-16 Is Asymmetrically Expressed (A) hlh-16 locus and translational (hlh-16trans::gfp) reporter gene structure. (B) Asymmetric expression of a transcriptional hlh-16prom::mcherry reporter (stIs10546; contains 2421 bp upstream of the start codon of the gene) and hlh-16trans::gfp (otEx4503; shown in A) in the SMDD/AIY and SIAD/SIBV lineages. Ventral view of embryos (anterior to the left) at epidermal enclosure (upper and lower panels show before and after terminal cell divisions, respectively) is shown. hlh-16prom::mcherry is fully asymmetric (100% left > right; n = 50); hlh-16trans::gfp is partially asymmetric (62% left expression > right, 32% left = right, 6% left < right; n = 50). (C) Lineage representation of hlh-16 expression. Green arrows point to a previously described Notch signaling event (see text) and the new Notch signaling event described in this paper. (D) Diagram showing a selected number of connected neurons from a navigation circuit [15-17]. Asymmetries in hlh-16 are shown in the same color code as in (C). ASE neurons are asymmetric based on the expression of many genes, including chemoreceptors. AWC is another sensory neuron that inputs into this circuit and is L/R asymmetric (this asymmetry is, however, stochastic).
  Name: Fig1.jpg
  Depict: Expr_pattern: Expr9608
    Anatomy: WBbt:0003961
      WBbt:0003963
      WBbt:0004971
      WBbt:0004972
      WBbt:0004977
      WBbt:0004978
      WBbt:0004987
      WBbt:0004989
  Acknowledgment: Template: Reprinted from <Journal_URL>, <Article_URL>, Copyright <Publication_year>, with permission from <Publisher_URL>.
    Publication_year: 2011
    Article_URL: DOI id 10.1016/j.cub.2011.06.016
    Journal_URL: CurrentBiology
    Publisher_URL: Elsevier
  Reference: WBPaper00039859