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WBPicture0000011057DescriptionFigure 7. ZTF-16 is expressed in glia and localizes to the nucleus. (A) A schematic of the ztf-16 promoter. The start codon (+1) is shown, as well as 4.6 kb of upstream promoter sequence (solid, horizontal line). The enhancer element used in B is between -4637 and -2536 relative to the +1 start site. (B) Fluorescence image (left) and fluorescence and DIC merged image (right) of an adult animal carrying a transgene containing the ztf-16 promoter region shown in A driving gfp expression (nsEx3001). Fluorescence is seen in the two AMsh glia (arrows), the AMso glia (arrowheads), and a pair of unidentified neurons anterior of the AMsh cell bodies. Expression is also observed in the PHsh and PHso glia in the tail (data not shown). (C) Localization of a ZTF-16::GFP fusion protein to the nucleus of the AMsh glia when expressed under a glia-specific promoter (nsEx1347). Arrows indicate the AMsh glia nucleus. Bar, 50 um. Anterior is up.
NameF7.large.jpg
DepictExpr_patternExpr9934
AnatomyWBbt:0003929
WBbt:0003931
WBbt:0003933
WBbt:0003935
Cellular_componentGO:0005634
AcknowledgmentTemplateWormBase thanks the journal <Journal_URL> for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Reprinted from <Journal_URL>, <Article_URL>. Copyright (<Publication_year>) with permission from <Publisher_URL>
Publication_year2012
Article_URLDOIid10.1534/genetics.111.137786
Journal_URLGenetics
Publisher_URLGSA
ReferenceWBPaper00040681