WormBase Tree Display for Interaction: WBInteraction000557086
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| WBInteraction000557086 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00001006 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00016120 | ||||
| Construct | WBCnstr00015686 | ||||
| WBGene00002632 | Interactor_type | Trans_regulator | |||
| Interaction_summary | "Time-lapse multi-photon analysis of a DLG-1-GFP fusion protein revealed that during an early phase of hypodermal morphogenesis (dorsal intercalation) in let-413(RNAi) embryos, DLG-1-GFP shows punctate localization to apical hypodermal junctions and is partly localized to the lateral membrane domain (Fig. 6a, e, f). In contrast, comparable wild-type embryos display a continuous pattern of DLG-1-GFP that is completely apical (Fig. 6b, g, h). As hypodermal morphogenesis proceeds, DLG-1-GFP accumulates at a narrow apical region of the hypodermal junctions of let-413(RNAi) embryos (Fig. 6c ,i, j), forming a pattern comparable with that of wild-type embryos (Fig. 6d, k, l)." | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [DLG-1::GFP] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000003 | ||
| Anatomy_term | WBbt:0005733 | ||||
| Subcellular_localization | apical junctions | ||||
| Paper | WBPaper00004961 | ||||
| Remark | Fig, 6 |
