WormBase Tree Display for Interaction: WBInteraction000556408
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| WBInteraction000556408 | Interaction_type | Physical | ProteinProtein | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00004034 | Interactor_type | Bait | |
| WBGene00000509 | Interactor_type | Target | |||
| Interaction_summary | "A short segment (212-GGIDNGAFHEHEI-224) of the V2 (linker) region of PKC3 creates a binding surface that interacts with the PTB domain of CKA1/CKA1S."; PKC-3 phosphorylates Ser-17 and Ser-65 in CKA-1. These residues are critical for proper localization of CKA-1 to the cell periphery: dual mutation to Ala results in localization to the periphery, whereas dual mutation to Glu blocks it, instead yielding accumulation of CKA-1 in the cytoplasm. | ||||
| Detection_method | Affinity_capture_Western | ||||
| Throughput | Low_throughput | ||||
| Paper | WBPaper00004639 |
