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WormBase Tree Display for Interaction: WBInteraction000554723

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Name Class

WBInteraction000554723Interaction_typePhysicalProteinProtein
InteractorInteractor_overlapping_geneWBGene00001184Interactor_typeBait
WBGene00002181Interactor_typeTarget
Interaction_summary"KAL-1/anosmin-1 mediates neurite branching as an autocrine co-factor with EGL-17/FGF through a receptor complex consisting of the conserved cell adhesion molecule SAX-7/L1CAM and the fibroblast growth factor receptor EGL-15/FGFR. This protein complex, which appears conserved in humans, requires the immunoglobulin (Ig) domains of SAX-7/L1CAM and the FN(III) domains of KAL-1/anosmin-1 for formation in vitro as well as function in vivo."
Detection_methodAffinity_capture_Western
ThroughputLow_throughput
PaperWBPaper00049508