WormBase Tree Display for Interaction: WBInteraction000535555
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| WBInteraction000535555 | Interaction_type | Genetic | Unilateral_enhancement | ||
|---|---|---|---|---|---|
| GI_module_one | Mono_phenotypic | ||||
| GI_module_two | Enhancing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00001184 | Interactor_type | Effector | |
| WBGene00003007 | Interactor_type | Affected | |||
| Variation_interactor | WBVar00089531 | Interactor_type | Effector | ||
| WBVar00143343 | Interactor_type | Affected | |||
| Interaction_summary | "To understand the genetic relationship between FGF signaling and the previously known Wnt polarity pathway components required for the wild-type vulval orientation, we constructed double mutants of egl-15(n484) with the canonical null alleles of lin-17 and lin-18 (Table 1). Because egl-15(n484) enhances the lin-18(e620) PRvl phenotype from 31 to 63% and has no effect on lin-17(n671), we believe the FGF pathway is working with the LIN-17 pathway to control vulval orientation." | ||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0002193 | ||||
| Paper | WBPaper00044058 | ||||
| Remark | Table 1 |
