WormBase Tree Display for Interaction: WBInteraction000535411
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| WBInteraction000535411 | Interaction_type | Genetic | Suppression | ||
|---|---|---|---|---|---|
| GI_module_two | Suppressing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00017769 | Interactor_type | Affected | |
| Molecule_interactor | WBMol:00004697 | Interactor_type | Effector | ||
| Interaction_summary | "hmgs-1 RNAi induces strong and robust phenotypes including paralysis, reduced pharyngeal pumping, and sterility (Fig S3B and Movie S1). In agreement with previous reports on the involvement of hmgs-1 in the mevalonate pathway (26, 27), these hmgs-1 RNAi phenotypes were fully rescued by mevalonate supplementation, indicating that C. elegans HMGS-1 is functionally equivalent to its ortholog HMGCS1 (Fig S3B and Movie S2)." | ||||
| Throughput | Low_throughput | ||||
| Interaction_RNAi | WBRNAi00107647 | ||||
| Interaction_phenotype | WBPhenotype:0000644 | ||||
| WBPhenotype:0000019 | |||||
| WBPhenotype:0000688 | |||||
| Paper | WBPaper00045692 |
