WormBase Tree Display for Interaction: WBInteraction000525298
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| WBInteraction000525298 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00006915 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr2407 | ||||
| Construct | WBCnstr00016253 | ||||
| WBGene00001243 | Interactor_type | Trans_regulator | |||
| Interaction_summary | In the control condition, VHA-6::mCherry was strongly expressed and localized on the intestinal apical membrane. A defect in mmBCFA biosynthesis [elo-5(RNAi)], sphingolipid biosynthesis [sptl-1(RNAi)], or intestinal apical polarity [chc-1(RNAi)], but not in TORC1 [let-363/TOR (RNAi)], caused a diffuse VHA-6::mCherry expression pattern with abnormal accumulation of the signal on large intestinal vesicles. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [VHA-6::mCherry] | ||||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0005792 | ||
| Subcellular_localization | apical membrane | ||||
| Interaction_RNAi | WBRNAi00103120 | ||||
| Paper | WBPaper00047025 |
