WormBase Tree Display for Interaction: WBInteraction000524008
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| WBInteraction000524008 | Interaction_type | Genetic | Enhancement | ||
|---|---|---|---|---|---|
| GI_module_two | Enhancing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00019726 | Interactor_type | Effector | |
| WBGene00001743 | Interactor_type | Affected | |||
| Variation_interactor | WBVar02125751 | Interactor_type | Affected | ||
| Interaction_summary | Knocking down the function of two Arf GEFs, EFA-6 and M02B7.5, which we name BRIS-1 for its homologs BRAG/IQSEC/Schizo, was able to enhance the grp-1 A/PVM phenotype, but did not induce a phenotype in animals that were wild type for grp-1. sing efa-6 and bris-1 mutations, we confirmed this enhancer effect in the grp-1 mutant. | ||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000829 | ||||
| WBProcess | WBbiopr:00000014 | ||||
| Paper | WBPaper00045516 | ||||
| Remark | bris-1 variation gk592726 |
