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WormBase Tree Display for Interaction: WBInteraction000520005

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Name Class

WBInteraction000520005Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00003026Interactor_typeTrans_regulated
TransgeneWBTransgene00000162
ConstructWBCnstr00000162
WBGene00000940Interactor_typeTrans_regulator
Variation_interactorWBVar01474238Interactor_typeTrans_regulator
Interaction_summaryIn wild-type worms, the lin-41 3'UTR_GFP signal was present in the L2 stage but decreased in adult animals. Although the signal was comparable for wild-type and dcs-1(qbc3) animals at the L2 stage, repression appeared enhanced in adult dcs-1 mutant animals relative to wild-type. This effect was accompanied by significantly decreased endogenous lin-41 mRNA levels in dcs-1(qbc3) rela- tive to wild-type adult animals.
Detection_methodConstruct
Reporter_gene[lin-41 3'-UTR::gfp]
Transgene
RT_PCR
Regulation_levelPost_transcriptional
PaperWBPaper00042195