WormBase Tree Display for Interaction: WBInteraction000519436
expand all nodes | collapse all nodes | view schema
WBInteraction000519436 | Interaction_type | Regulatory | Change_of_expression_level | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene (2) | ||||
Other_interactor | fasting | Interactor_type | Trans_regulator | ||
Variation_interactor | WBVar00088251 | Interactor_type | Trans_regulator | ||
Interaction_summary | While daf-16 targeting gene dod-6 mRNA levels were markedly increased in response to fasting in wild-type worms, their increases were significantly suppressed in the loss-of-function mutant of kgb-1 (kgb-1(km21)), suggesting the possibility that KGB-1 signaling is required for the fasting-induced activation of DAF- 16. | ||||
Detection_method | RT_PCR | ||||
Regulation_level | Transcriptional | ||||
Paper | WBPaper00041960 |