WormBase Tree Display for Interaction: WBInteraction000517532
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| WBInteraction000517532 | Interaction_type | Genetic | Suppression | ||
|---|---|---|---|---|---|
| GI_module_two | Suppressing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00006732 | Interactor_type | Effector | |
| WBGene00004457 | Interactor_type | Affected | |||
| Variation_interactor | WBVar00296567 | Interactor_type | Effector | ||
| WBVar00088149 | Interactor_type | Affected | |||
| Interaction_summary | In an rpm-1(lf) background, mutations in uev-3 can ameliorate the defects in motor neuron synapses and touch axon patterning. | ||||
| Double mutants show significant suppression of the rpm-1 phenotype, increasing SNB-1::GFP puncta number in the dorsal cord from that seen in rpm-1 mutants alone. | |||||
| The uev-3 mutation significantly suppressed rpm-1. | |||||
| uev-3(ju639) has a slightly stronger suppression effect on the mechanosensory neuron phenotypes than uev-3(ju587). | |||||
| Inrpm-1; uev-3 mutant strains, the transcript levels of cebp-1 are comparable to wild-type levels. | |||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0000181 | ||||
| WBPhenotype:0000905 | |||||
| WBPhenotype:0000961 | |||||
| WBPhenotype:0000616 | |||||
| WBPhenotype:0000114 | |||||
| Paper | WBPaper00036408 |
