WormBase Tree Display for Gene: WBGene00050876
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| WBGene00050876 | Identity | Version | 1 | |||||
|---|---|---|---|---|---|---|---|---|
| Name | CGC_name | bah-2 | Person_evidence | WBPerson125 | ||||
| Public_name | bah-2 | |||||||
| Species | Caenorhabditis elegans | |||||||
| History | Version_change | 1 | 31 Jul 2007 09:27:58 | WBPerson2970 | Event | Created | ||
| Status | Live | |||||||
| Gene_info | Gene_class | bah | ||||||
| Allele | WBVar00879692 | Inferred_automatically | From strain object: CB7201 | |||||
| From strain object: CB7401 | ||||||||
| From strain object: CB7403 | ||||||||
| From strain object: CB7410 | ||||||||
| WBVar00000544 | Inferred_automatically | From strain object: DC7 | ||||||
| WBVar00000545 | ||||||||
| Strain | WBStrain00004748 | |||||||
| WBStrain00004753 | ||||||||
| WBStrain00004754 | ||||||||
| WBStrain00004755 | ||||||||
| WBStrain00005602 | ||||||||
| Structured_description | Concise_description | bah-2 was identified in screens for mutants that were resistant to the attachment of biofilms produced by bacteria such as Yersinia pestis and Yersinia pseudotuberculosis; bah-2 most likely encodes a surface cuticle component required for biofilm formation; bah-2 mutant cuticles are also fragile compared to wild-type. | Paper_evidence | WBPaper00029153 | ||||
| Curator_confirmed | WBPerson324 | |||||||
| Date_last_updated | 14 Oct 2011 00:00:00 | |||||||
| Disease_info | Experimental_model | DOID:104 | Homo sapiens | Paper_evidence | WBPaper00006215 | |||
| Curator_confirmed | WBPerson324 | |||||||
| Date_last_updated | 08 Nov 2023 00:00:00 | |||||||
| Disease_relevance | C. elegans is being used as a model system to identify and study the genes required for the formation of bacterial biofilms in the host; the inherent resistance of biofilms to antimicrobial agents like phagocytes, antibiotics etc, are the root cause of chronic bacterial infections; the bah genes in elegans, bah-1, bah-2 and bah-3 are required for infection of elegans by biofilm producing bacteria Yersinia pestis and Yersinia pseudotuberculosis, which bind to the C. elegans surface, predominantly on the head. | Homo sapiens | Paper_evidence | WBPaper00035152 | ||||
| WBPaper00006215 | ||||||||
| Curator_confirmed | WBPerson324 | |||||||
| Date_last_updated | 14 Oct 2011 00:00:00 | |||||||
| Models_disease_in_annotation | WBDOannot00000021 | |||||||
| Experimental_info | Interaction | WBInteraction000052458 | ||||||
| Reference | WBPaper00029153 | |||||||
| WBPaper00031925 | ||||||||
| WBPaper00048269 | ||||||||
| WBPaper00051834 | ||||||||
| Method | Gene |
