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WormBase Tree Display for Gene: WBGene00022189

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Name Class

WBGene00022189SMapS_parentSequenceY71H2AR
IdentityVersion1
NameSequence_nameY71H2AR.2
Molecular_nameY71H2AR.2
Y71H2AR.2.1
CE54189
Other_nameY71H2AR.aCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y71H2AR.2Accession_evidenceNDBBX284603
Public_nameY71H2AR.2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (35)
StrainWBStrain00037431
RNASeq_FPKM (74)
GO_annotation00091797
00091798
00091799
00091800
00126359
00126360
Ortholog (51)
Paralog (29)
Structured_descriptionAutomated_descriptionPredicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Down syndrome; cerebrovascular disease (multiple); and pycnodysostosis. Is an ortholog of human CTSK (cathepsin K) and CTSS (cathepsin S).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2545)
DOID:2378Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2545)
DOID:3407Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2545)
DOID:14250Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2545)
DOID:870Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2545)
DOID:0080038Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2536)
DOID:10941Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:2536,HGNC:2545)
Molecular_infoCorresponding_CDSY71H2AR.2
Corresponding_CDS_historyY71H2AR.2:wp275
Corresponding_transcriptY71H2AR.2.1
Associated_featureWBsf1014465
Experimental_infoRNAi_resultWBRNAi00115192Inferred_automaticallyRNAi_primary
WBRNAi00076842Inferred_automaticallyRNAi_primary
WBRNAi00021367Inferred_automaticallyRNAi_primary
WBRNAi00065289Inferred_automaticallyRNAi_primary
WBRNAi00058255Inferred_automaticallyRNAi_primary
Expr_patternExpr1161674
Expr2026571
Microarray_results (11)
Expression_cluster (92)
Map_infoPositivePositive_cloneY71H2ARInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIII-9.70008
ReferenceWBPaper00038491
WBPaper00055090
MethodGene