WormBase Tree Display for Gene: WBGene00021945

WBGene00021945 SMap: S_parent: Sequence: Y55F3BR
  Identity: Version: 2
    Name: CGC_name: lem-4 Paper_evidence: WBPaper00041279
      Sequence_name: Y55F3BR.8
      Molecular_name: Y55F3BR.8a
        Y55F3BR.8a.1
        CE31657
        Y55F3BR.8b
        CE37730
        Y55F3BR.8b.1
      Other_name: Y55F3BR.a Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        Y55F3BR.b Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        Y55F3BR.c Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        Y55F3BR.i Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_Y55F3BR.8 Accession_evidence: NDB BX284604
      Public_name: lem-4
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:05 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 24 Sep 2012 09:17:58 WBPerson2970 Name_change: CGC_name: lem-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lem
    Allele (134)
    Strain: WBStrain00049430
      WBStrain00054622
    RNASeq_FPKM (74)
    GO_annotation (20)
    Ortholog (34)
    Structured_description: Automated_description: Enables protein phosphatase 2A binding activity. Involved in mitotic nuclear membrane reassembly; negative regulation of phosphorylation; and positive regulation of protein dephosphorylation. Located in nuclear envelope. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 16. Is an ortholog of human ANKLE2 (ankyrin repeat and LEM domain containing 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070289 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:29101)
  Molecular_info: Corresponding_CDS: Y55F3BR.8a
      Y55F3BR.8b
    Corresponding_CDS_history: Y55F3BR.8:wp82
      Y55F3BR.8:wp134
    Corresponding_transcript: Y55F3BR.8a.1
      Y55F3BR.8b.1
    Other_sequence: CJC15831_1
      CRC09418_1
    Associated_feature: WBsf651632
      WBsf229725
      WBsf229726
  Experimental_info: RNAi_result: WBRNAi00037526 Inferred_automatically: RNAi_primary
      WBRNAi00057551 Inferred_automatically: RNAi_primary
      WBRNAi00021038 Inferred_automatically: RNAi_primary
      WBRNAi00021037 Inferred_automatically: RNAi_primary
      WBRNAi00061942 Inferred_automatically: RNAi_primary
      WBRNAi00057550 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr10588
      Expr1016272
      Expr1039654
      Expr1160984
      Expr2013046
      Expr2031278
    Drives_construct: WBCnstr00017017
    Construct_product: WBCnstr00017017
    Antibody: WBAntibody00002348
    Microarray_results (29)
    Expression_cluster (125)
    Interaction: WBInteraction000518816
      WBInteraction000543018
      WBInteraction000543078
      WBInteraction000553905
      WBInteraction000556582
  Map_info: Map: IV Position: -23.2395
    Positive: Positive_clone: Y55F3BR Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00041279
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene