WormBase Tree Display for Gene: WBGene00021127
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WBGene00021127 | SMap | S_parent | Sequence | W10C8 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Allele (30) | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00033786 | |||||
Ortholog (43) | ||||||
Paralog (45) | ||||||
Structured_description | Automated_description | Enriched in excretory gland cell; pharyngeal cell; and touch receptor neurons based on tiling array; microarray; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and rrf-3 based on microarray; RNA-seq; tiling array; and proteomic studies. Is affected by thirteen chemicals including rotenone; stavudine; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in asthma and ovarian cancer. Human GSTA1 enables several functions, including glutathione peroxidase activity; glutathione transferase activity; and steroid delta-isomerase activity. Is predicted to encode a protein with the following domains: Glutathione S-transferase, C-terminal domain superfamily; Glutathione S-transferase, C-terminal; and Glutathione S-transferase, C-terminal domain. Is an ortholog of several human genes including GSTA1 (glutathione S-transferase alpha 1); GSTA2 (glutathione S-transferase alpha 2); and GSTA3 (glutathione S-transferase alpha 3). | Paper_evidence | WBPaper00065943 | ||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:2841 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4626) | |
DOID:2394 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4626) | |||
Molecular_info | Corresponding_CDS | W10C8.4a | ||||
W10C8.4c | ||||||
W10C8.4d | ||||||
Corresponding_CDS_history | W10C8.4b:wp96 | |||||
W10C8.4b:wp245 | ||||||
W10C8.4b:wp274 | ||||||
Corresponding_transcript | W10C8.4a.1 | |||||
W10C8.4c.1 | ||||||
W10C8.4d.1 | ||||||
Other_sequence | EX553359.1 | |||||
Acan_isotig15788 | ||||||
FD515160.1 | ||||||
Tcol_isotig12548 | ||||||
CSC01285_1 | ||||||
ACC11024_1 | ||||||
Associated_feature | WBsf648990 | |||||
WBsf983003 | ||||||
WBsf983004 | ||||||
WBsf219069 | ||||||
Experimental_info (5) | ||||||
Map_info | Positive | Positive_clone | W10C8 | Inferred_automatically | From sequence, transcript, pseudogene data | |
Interpolated_map_position | I | -5.31164 | ||||
Method | Gene |