WormBase Tree Display for Gene: WBGene00020788
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WBGene00020788 | SMap | S_parent | Sequence | T25B6 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | nep-22 | Person_evidence | WBPerson260 | |||
Sequence_name | T25B6.2 | ||||||
Molecular_name | T25B6.2 | ||||||
T25B6.2.1 | |||||||
CE14174 | |||||||
Other_name | CELE_T25B6.2 | Accession_evidence | NDB | BX284606 | |||
Public_name | nep-22 | ||||||
DB_info | Database | AceView | gene | XJ655 | |||
WormQTL | gene | WBGene00020788 | |||||
WormFlux | gene | WBGene00020788 | |||||
NDB | locus_tag | CELE_T25B6.2 | |||||
Panther | gene | CAEEL|WormBase=WBGene00020788|UniProtKB=Q22763 | |||||
family | PTHR11733 | ||||||
NCBI | gene | 181144 | |||||
RefSeq | protein | NM_077127.5 | |||||
TREEFAM | TREEFAM_ID | TF318791 | |||||
TrEMBL | UniProtAcc | Q22763 | |||||
UniProt_GCRP | UniProtAcc | Q22763 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | nep | ||||||
Allele (69) | |||||||
Strain | WBStrain00033138 | ||||||
WBStrain00037406 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (13) | |||||||
Ortholog (31) | |||||||
Paralog (24) | |||||||
Structured_description | Concise_description | nep-22 encodes two isoforms of a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; NEP-22 is orthologous to Ac-mep-1, a gut luminal neprilysin which is specifically expressed in the adult life stage of Ancylostoma caninum hookworms, and whose protein product is localized to the microvilli of the gastrointestinal tract, suggesting a role in digestion. | Paper_evidence (3) | ||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 27 Mar 2014 00:00:00 | ||||||
Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | T25B6.2 | |||||
Corresponding_CDS_history | T25B6.2a:wp142 | ||||||
T25B6.2b:wp142 | |||||||
Corresponding_transcript | T25B6.2.1 | ||||||
Other_sequence (102) | |||||||
Associated_feature | WBsf648394 | ||||||
WBsf236116 | |||||||
WBsf236117 | |||||||
WBsf236118 | |||||||
Experimental_info | RNAi_result | WBRNAi00054097 | Inferred_automatically | RNAi_primary | |||
WBRNAi00000575 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00035945 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089168 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00019187 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr1019959 | ||||||
Expr1039054 | |||||||
Expr1157641 | |||||||
Expr2013967 | |||||||
Expr2032206 | |||||||
Drives_construct | WBCnstr00024887 | ||||||
Construct_product | WBCnstr00024887 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (260) | |||||||
Interaction (40) | |||||||
Map_info | Map | X | Position | 0.573562 | |||
Positive | Positive_clone | T25B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00011415 | ||||||
WBPaper00011735 | |||||||
WBPaper00029046 | |||||||
WBPaper00037777 | |||||||
WBPaper00055090 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |