WormBase Tree Display for Gene: WBGene00020788
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WBGene00020788 | SMap | S_parent | Sequence | T25B6 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | nep | |||||
Allele (69) | ||||||
Strain | WBStrain00033138 | |||||
WBStrain00037406 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (13) | ||||||
Ortholog (31) | ||||||
Paralog (24) | ||||||
Structured_description | Concise_description | nep-22 encodes two isoforms of a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; NEP-22 is orthologous to Ac-mep-1, a gut luminal neprilysin which is specifically expressed in the adult life stage of Ancylostoma caninum hookworms, and whose protein product is localized to the microvilli of the gastrointestinal tract, suggesting a role in digestion. | Paper_evidence (3) | |||
Curator_confirmed | WBPerson567 | |||||
Date_last_updated | 27 Mar 2014 00:00:00 | |||||
Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Located in membrane raft. | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Molecular_info | Corresponding_CDS | T25B6.2 | ||||
Corresponding_CDS_history | T25B6.2a:wp142 | |||||
T25B6.2b:wp142 | ||||||
Corresponding_transcript | T25B6.2.1 | |||||
Other_sequence (102) | ||||||
Associated_feature | WBsf648394 | |||||
WBsf236116 | ||||||
WBsf236117 | ||||||
WBsf236118 | ||||||
Experimental_info | RNAi_result | WBRNAi00054097 | Inferred_automatically | RNAi_primary | ||
WBRNAi00000575 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00035945 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00089168 | Inferred_automatically | RNAi_primary | ||||
WBRNAi00019187 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr1019959 | |||||
Expr1039054 | ||||||
Expr1157641 | ||||||
Expr2013967 | ||||||
Expr2032206 | ||||||
Drives_construct | WBCnstr00024887 | |||||
Construct_product | WBCnstr00024887 | |||||
Microarray_results (19) | ||||||
Expression_cluster (260) | ||||||
Interaction (40) | ||||||
Map_info | Map | X | Position | 0.573562 | ||
Positive | Positive_clone | T25B6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference | WBPaper00011415 | |||||
WBPaper00011735 | ||||||
WBPaper00029046 | ||||||
WBPaper00037777 | ||||||
WBPaper00055090 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |