WormBase Tree Display for Gene: WBGene00020296
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| WBGene00020296 | SMap | S_parent | Sequence | T07A9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 4 | |||||||
| Name | CGC_name | rrp-8 | Paper_evidence | WBPaper00053873 | |||||
| Sequence_name | T07A9.8 | ||||||||
| Molecular_name | T07A9.8 | ||||||||
| T07A9.8.1 | |||||||||
| CE17217 | |||||||||
| Other_name | rram-1 | Paper_evidence | WBPaper00053637 | ||||||
| susi-2 | Person_evidence | WBPerson6615 | |||||||
| CELE_T07A9.8 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | rrp-8 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 07 Jun 2018 14:30:09 | WBPerson1983 | Name_change | CGC_name | rrp-8 | ||||
| 3 | 11 Dec 2018 16:50:34 | WBPerson1983 | Name_change | CGC_name | rrp-8 | ||||
| Other_name | rram-1 | ||||||||
| 4 | 02 Jul 2019 16:40:16 | WBPerson1983 | Name_change | Other_name | susi-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rrp | ||||||||
| Allele (39) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (20) | |||||||||
| Contained_in_operon | CEOP4020 | ||||||||
| Ortholog (35) | |||||||||
| Structured_description | Concise_description | RRP-8 is an ortholog of human RRP8 (ribosomal RNA processing 8, methyltransferase, (yeast)); RRP-8 was identified as a negative regulator of endo-siRNA generation in C. elegans by a clonal screen (suppressor of siRNA gene 2, susi-2); RRP-8 contains an methyltransferase-like domain (MLD) and displays methyltransferase activity at A674 in 26S rRNA; in eri-1(mg366);GFP::NRDE-3 worms, the mutated susi-2 could redistribute NRDE-3 from the cytoplasm to the nucleus. | Paper_evidence | WBPaper00053873 | |||||
| WBPaper00057242 | |||||||||
| Person_evidence | WBPerson3638 | ||||||||
| WBPerson28639 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 29 Aug 2019 00:00:00 | ||||||||
| Automated_description | Predicted to enable methylated histone binding activity. Predicted to be involved in cellular response to glucose starvation; rDNA heterochromatin formation; and regulation of transcription by glucose. Predicted to be located in nucleolus. Predicted to be part of chromatin silencing complex and rDNA heterochromatin. Expressed widely. Is an ortholog of human RRP8 (ribosomal RNA processing 8). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T07A9.8 | |||||||
| Corresponding_transcript | T07A9.8.1 | ||||||||
| Other_sequence (32) | |||||||||
| Associated_feature | WBsf227840 | ||||||||
| Experimental_info | RNAi_result (15) | ||||||||
| Expr_pattern | Expr13731 | ||||||||
| Expr14855 | |||||||||
| Expr14856 | |||||||||
| Expr1019711 | |||||||||
| Expr1038841 | |||||||||
| Expr1156318 | |||||||||
| Expr2005955 | |||||||||
| Expr2024172 | |||||||||
| Drives_construct | WBCnstr00025237 | ||||||||
| WBCnstr00039957 | |||||||||
| WBCnstr00041559 | |||||||||
| WBCnstr00041560 | |||||||||
| Construct_product | WBCnstr00025237 | ||||||||
| WBCnstr00039957 | |||||||||
| WBCnstr00041560 | |||||||||
| Antibody | WBAntibody00002812 | ||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (82) | |||||||||
| SAGE_tag | SAGE:tatagagttt | Strand | Antisense | ||||||
| SAGE:aagtaatcggttagctc | Strand | Antisense | |||||||
| SAGE:gcgtaataag | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:aagtaatcgg | Strand | Antisense | |||||||
| SAGE:gacgtttctttttcttt | Strand | Antisense | |||||||
| SAGE:gacgtttctt | Strand | Antisense | |||||||
| SAGE:tactggttct | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:atgatggaattcaagaa | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:atgatggaat | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| SAGE:gcgtaataaggtccgta | Strand | Sense | |||||||
| Unambiguously_mapped | |||||||||
| Interaction (132) | |||||||||
| Map_info | Map | IV | Position | -26.2064 | |||||
| Positive | Positive_clone | T07A9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (11) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
