WormBase Tree Display for Gene: WBGene00017842
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WBGene00017842 | SMap | S_parent | Sequence | F26G1 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name (5) | |||||||||
DB_info | Database | AceView | gene | 2F66 | |||||
WormQTL | gene | WBGene00017842 | |||||||
WormFlux | gene | WBGene00017842 | |||||||
NDB | locus_tag | CELE_F26G1.6 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00017842|UniProtKB=Q19831 | |||||||
family | PTHR11733 | ||||||||
NCBI | gene | 173824 | |||||||
RefSeq | protein | NM_001377790.1 | |||||||
NM_001377789.2 | |||||||||
TrEMBL | UniProtAcc | A0A5S9MNU9 | |||||||
A0A5S9MND8 | |||||||||
UniProt_GCRP | UniProtAcc | A0A5S9MNU9 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 10 Feb 2012 15:49:10 | WBPerson2970 | Name_change | CGC_name | nep-12 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | nep | ||||||||
Allele (139) | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (12) | |||||||||
Ortholog (46) | |||||||||
Paralog (24) | |||||||||
Structured_description | Concise_description | F26G1.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while F26G1.6 has no clear orthologs in other organisms, it falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes). | Paper_evidence | WBPaper00004584 | |||||
WBPaper00013276 | |||||||||
Curator_confirmed | WBPerson567 | ||||||||
Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
Automated_description | Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane. Is an ortholog of human KEL (Kell metallo-endopeptidase (Kell blood group)). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F26G1.6a | |||||||
F26G1.6b | |||||||||
Corresponding_CDS_history | F26G1.6:wp107 | ||||||||
F26G1.6:wp130 | |||||||||
F26G1.6:wp274 | |||||||||
Corresponding_transcript | F26G1.6a.1 | ||||||||
F26G1.6b.1 | |||||||||
Other_sequence (11) | |||||||||
Associated_feature | WBsf650014 | ||||||||
WBsf650015 | |||||||||
WBsf665476 | |||||||||
WBsf665477 | |||||||||
WBsf717656 | |||||||||
WBsf717657 | |||||||||
WBsf987696 | |||||||||
WBsf987697 | |||||||||
WBsf1012126 | |||||||||
WBsf1012127 | |||||||||
Experimental_info (7) | |||||||||
Map_info | Map | II | Position | -3.0646 | |||||
Positive | Positive_clone | F26G1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00011735 | ||||||||
WBPaper00019195 | |||||||||
WBPaper00064648 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |