WormBase Tree Display for Gene: WBGene00017082
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WBGene00017082 | SMap | S_parent | Sequence | DC2 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Allele (48) | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation | 00100722 | |||||
Ortholog (33) | ||||||
Paralog (11) | ||||||
Structured_description | Automated_description | Enriched in several structures, including ABplpppapa; ABprpppapa; anal sphincter muscle; rectal epithelial cell; and sensory neurons based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eighteen chemicals including TPEN; Alovudine; and stavudine based on RNA-seq; proteomic; and microarray studies. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; and esophagus squamous cell carcinoma. Human WWOX enables enzyme binding activity and identical protein binding activity. Is predicted to encode a protein with the following domains: Short-chain dehydrogenase/reductase SDR; short chain dehydrogenase; and NAD(P)-binding domain superfamily. Is an ortholog of human WWOX (WW domain containing oxidoreductase). | Paper_evidence | WBPaper00065943 | ||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:3748 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | |
DOID:5041 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | |||
DOID:0080452 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | |||
DOID:0080060 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | |||
DOID:1749 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:12799) | |||
Molecular_info | Corresponding_CDS | DC2.5a | ||||
Corresponding_CDS_history | DC2.5:wp88 | |||||
DC2.5:wp125 | ||||||
DC2.5:wp188 | ||||||
Corresponding_transcript | DC2.5b | |||||
DC2.5a.1 | ||||||
Other_sequence | Oden_isotig21742 | |||||
Associated_feature | WBsf652436 | |||||
WBsf668708 | ||||||
WBsf999097 | ||||||
WBsf999098 | ||||||
WBsf999099 | ||||||
WBsf1019030 | ||||||
WBsf1019031 | ||||||
WBsf233243 | ||||||
Experimental_info | RNAi_result | WBRNAi00043540 | Inferred_automatically | RNAi_primary | ||
WBRNAi00012615 | Inferred_automatically | RNAi_primary | ||||
Expr_pattern | Expr1025881 | |||||
Expr1037341 | ||||||
Expr1147532 | ||||||
Expr2002107 | ||||||
Expr2020332 | ||||||
Microarray_results (15) | ||||||
Expression_cluster (212) | ||||||
Interaction | WBInteraction000471081 | |||||
WBInteraction000585656 | ||||||
Map_info | Positive | Positive_clone | DC2 | Inferred_automatically | From sequence, transcript, pseudogene data | |
Interpolated_map_position | V | -20.0099 | ||||
Reference (2) | ||||||
Method | Gene |