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WormBase Tree Display for Gene: WBGene00016772

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Name Class

WBGene00016772SMapS_parentSequenceC49D10
IdentityVersion2
NameCGC_namenhr-166Person_evidenceWBPerson600
Sequence_nameC49D10.2
Molecular_nameC49D10.2
C49D10.2.1
CE08843
Other_nameCELE_C49D10.2Accession_evidenceNDBBX284602
Public_namenhr-166
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:57WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
222 Jul 2005 10:29:12WBPerson2970Name_changeCGC_namenhr-166
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnhr
Allele (112)
StrainWBStrain00036538
WBStrain00036539
WBStrain00036685
RNASeq_FPKM (74)
GO_annotation00028352
00028353
00028354
00028355
00122315
00122316
00122317
00122318
Ortholog (25)
Paralog (218)
Structured_descriptionAutomated_descriptionPredicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons. Human ortholog(s) of this gene implicated in cholestasis (multiple); liver disease (multiple); and non-alcoholic steatohepatitis. Is an ortholog of human NR1H4 (nuclear receptor subfamily 1 group H member 4) and NR1I3 (nuclear receptor subfamily 1 group I member 3).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:12236Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7967)
DOID:0070225Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7967)
DOID:13619Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7967)
DOID:0080547Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7967)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:7967)
Molecular_infoCorresponding_CDSC49D10.2
Corresponding_transcriptC49D10.2.1
Associated_featureWBsf1011975
WBsf221055
WBsf221056
Transcription_factorWBTranscriptionFactor000974
Experimental_infoRNAi_resultWBRNAi00115878Inferred_automaticallyRNAi_primary
WBRNAi00012139Inferred_automaticallyRNAi_primary
WBRNAi00115770Inferred_automaticallyRNAi_primary
WBRNAi00029979Inferred_automaticallyRNAi_primary
WBRNAi00042799Inferred_automaticallyRNAi_primary
Expr_patternExpr7482
Expr1018827
Expr1146780
Expr2014066
Expr2032306
Drives_constructWBCnstr00012626
WBCnstr00027814
Construct_productWBCnstr00027814
Microarray_results (18)
Expression_cluster (38)
Interaction (32)
Map_infoMapIIPosition-6.0317Error0.013177
PositivePositive_cloneC49D10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5354
Pseudo_map_position
ReferenceWBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene